Protein Alignment CG45062 and SERCA

DIOPT Version :9

• Sequence 1: NP_001286726.1
• Gene: CG45062 / 19835139
• FlyBaseID: FBgn0266432
• Length: 794
• Species: Drosophila melanogaster
• Sequence 2: NP_726381.1
• Gene: SERCA / 49297
• FlyBaseID: FBgn0263006
• Length: 1020
• Species: Drosophila melanogaster
• Alignment Length: 872
• Identity: 196/872 - (22%)
• Similarity: 364/872 - (41%)
• Gaps: 183/872 - (20%)

  Fly    13 NMGLACTHAISGIGFAVALACGRNTEVGSM-TDLCFKERSRSRSQKHQKQISYYM-LLVAIVCFI 75
            |:..:.|:..:|....|.:..|.:|.:|.: |::...|..::..|:...:....: .:::::|..
  Fly   206 NILFSGTNVAAGKARGVVIGTGLSTAIGKIRTEMSETEEIKTPLQQKLDEFGEQLSKVISVICVA 270

  Fly    76 LLFLTTGF----EHGH-------IVYEVNLSLLIGLTPVYLPFILYWGLRRTRKEMGRKQCHVRN 129
            :..:..|.    .||.       ..:::.::|.:...|..||.::...|....:.|.:|...||:
  Fly   271 VWAINIGHFNDPAHGGSWIKGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRS 335

  Fly   130 LRATCTLGLSTVIVSDLVGTMTKRRMRVSEIFV-------DMGLLSVDNLDVSAQSP-------- 179
            |.:..|||.::||.||..||:|..:|.||.:|:       |...|..: :..|...|
  Fly   336 LPSVETLGCTSVICSDKTGTLTTNQMSVSRMFIFDKVEGNDSSFLEFE-MTGSTYEPIGEVFLNG 399

  Fly   180 ---------RFIELIRASVLCNDAVICPGNIGVPKMQKDMYGNILDIALL------------KFG 223
                     ...||....::|||:.|   :....|...:..|...:.||:            |.|
  Fly   400 QRIKAADYDTLQELSTICIMCNDSAI---DYNEFKQAFEKVGEATETALIVLAEKLNSFSVNKSG 461

  Fly   224 LMILPSIDLLRHDHEKVANKHYN---SEDKVQVTVHRTRDADGHLKL--VLLMKGHCEVVIRRCS 283
            |....:....|.:.|....|.:.   |.|:..::.:.|......|..  .|.:||..|.|:.||:
  Fly   462 LDRRSAAIACRGEIETKWKKEFTLEFSRDRKSMSSYCTPLKASRLGTGPKLFVKGAPEGVLERCT 526

  Fly   284 TFAIRDEELPLDEQLQEIILSLADGLLEAGRH-VRAFAYKELS-----DELEFRRFSQVNTGLEG 342
            ...:...::||...|:..||:|. |....||. :|..|.....     ||::.           |
  Fly   527 HARVGTTKVPLTSALKAKILALT-GQYGTGRDTLRCLALAVADSPMKPDEMDL-----------G 579

  Fly   343 GEYKYRDYLAVDTYSLRFLGMIATYNPPRSTIPKAVDRCRAAGIKLIVVTQRKPKMAKALAVDVG 407
            ...|:..|    ..:|.|:|::...:|||..:..::.|||||||::||:|......|:|:...:|
  Fly   580 DSTKFYQY----EVNLTFVGVVGMLDPPRKEVFDSIVRCRAAGIRVIVITGDNKATAEAICRRIG 640

  Fly   408 ILPAPSDT----FQAVNLKRMPPT---AEVVDMSQYADEKPQHQRRHIEQLILNQQDLVCAATST 465
            :.....||    :.......:.||   |.|.....::..:|||:.:.:|.|
  Fly   641 VFAEDEDTTGKSYSGREFDDLSPTEQKAAVARSRLFSRVEPQHKSKIVEFL-------------- 691

  Fly   466 DQLHWIADACRRLGAVVSVIGGTLHDTPAMRSSHVGVAKYGSAVMCEASADLILLDTSFATLVSV 530
                      :.:..:.::.|..::|.||::.:.:|:|......:.:::|:::|.|.:|:::||.
  Fly   692 ----------QSMNEISAMTGDGVNDAPALKKAEIGIAMGSGTAVAKSAAEMVLADDNFSSIVSA 746

  Fly   531 VGDSRLLFENLKKALAYCLATNICNILVYLFFFLLGIPLYIHIMDELILAFL--VNLV----PAL 589
            |.:.|.::.|:|:.:.|.:::||..::.......||:|      :.||...|  ||||    ||.
  Fly   747 VEEGRAIYNNMKQFIRYLISSNIGEVVSIFLTAALGLP------EALIPVQLLWVNLVTDGLPAT 805

  Fly   590 TLIYEPPEENLMLQMPKVYDDFLLNSRLFFVSHILVG------TIEAAAVFMTYFVFMADKGFLP 648
            .|.:.||:.::|.:.|:..|:.|::..||| .::.:|      |:.|||   .:||| :|:|  |
  Fly   806 ALGFNPPDLDIMEKPPRKADEGLISGWLFF-RYMAIGFYVGAATVGAAA---WWFVF-SDEG--P 863

  Fly   649 RTLVALNIAWHDDMLDDITDSFGQEWSSEARRQLECQVSS------LCLMSLAVMQCTNL----- 702
            : |....:..|...|..     |.|:     :.::|::.|      :.|..|..::..|.
  Fly   864 K-LSYWQLTHHLSCLGG-----GDEF-----KGVDCKIFSDPHAMTMALSVLVTIEMLNAMNSLS 917

  Fly   703 ----VLTKTGRANLLAHGFRNWLL-SLAVLLLICLCVQLCIMDSTVC----LRLEGTNELHFGHF 758
                ::|.....||       ||: |:|:...:...:....:.|||.    |..|.
  Fly   918 ENQSLITMPPWCNL-------WLIGSMALSFTLHFVILYVDVLSTVFQVTPLSAEE--------- 966

  Fly   759 LLTNCPFMILLVFIETTRRYFIRLFPD 785
            .:|...|.|.:|.::.|.::..|...|
  Fly   967 WITVMKFSIPVVLLDETLKFVARKIAD 993

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG45062	NP_001286726.1	E1-E2_ATPase	<13..132	CDD:278548	24/131 (18%)
		Cation_ATPase	190..284	CDD:289987	25/110 (23%)
		Cation_ATPase_C	582..777	CDD:295563	55/226 (24%)
SERCA	NP_726381.1	P-type_ATPase_SERCA	5..989	CDD:319778	194/866 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438591
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	282	1.000	Inparanoid score	I96
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42861
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.990