Protein Alignment CG45062 and atp2b3a

DIOPT Version :10

• Sequence 1: NP_001286726.1
• Gene: CG45062 / 19835139
• FlyBaseID: FBgn0266432
• Length: 794
• Species: Drosophila melanogaster
• Sequence 2: XP_005166875.1
• Gene: atp2b3a / 436745
• ZFINID: ZDB-GENE-040718-174
• Length: 1299
• Species: Danio rerio
• Alignment Length: 679
• Identity: 166/679 - (24%)
• Similarity: 301/679 - (44%)
• Gaps: 145/679 - (21%)

  Fly    35 RNTEVGSMTDLCFKERSRSRSQKHQKQI---------------SYYMLLVAIVCFILLFLTTGFE 84
            ::.|.|.:.:   ||:.::...|.:|.:               ...|..:.::..:|.|:...|
Zfish   357 KSAEGGEVEE---KEKKKASVPKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILMLYFVIKTF- 417

  Fly    85 HGHIVYE--------------------VNLSLLIGLTPVYLPFILYWGLRRTRKEMGRKQCHVRN 129
               ||::                    :.:::|:...|..||..:...|..:.|:|.:....||:
Zfish   418 ---IVHKQPWLTECTPIYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRH 479

  Fly   130 LRATCTLGLSTVIVSDLVGTMTKRRMRVSEIFVDMGLLSVDNL--DVSAQ---SPRFIELIRASV 189
            |.|..|:|.:|.|.||..||:|..||.|.:|::.      |.|  |:...   :||.:|||.:::
Zfish   480 LDACETMGNATAICSDKTGTLTTNRMTVVQIYIG------DQLFRDIPTPDQINPRTLELISSAI 538

  Fly   190 LCNDAV---ICPGNI--GVPKMQKDMYGNILDIALLKFGLMILPSIDLLRHDHEKVANK------ 243
            ..|.|.   |.|.:.  |:||    ..||..:.|||  ||:    :| |:.|::.|..:
Zfish   539 AVNCAYTSKIMPADKEGGLPK----QVGNKTECALL--GLV----LD-LKQDYQAVREQIPEELL 592

  Fly   244 ----HYNSEDKVQVTVHRTRDADGHLKLVLLMKGHCEVVIRRCSTFAIRDEEL------PLDEQL 298
                .:||..|...||  .:..||..:  |..||..|:::::||....||.|.      ..||.:
Zfish   593 YKVYTFNSVRKSMSTV--IQMPDGSFR--LYSKGASEILLKKCSFILSRDGEARAFRARDKDEMV 653

  Fly   299 QEIILSLA-DGLLEAGRHVRAFAYKEL-SDEL-EFRRFSQVNTGLEGGEYKYRDYLAVDTYSLRF 360
            :::|..:| |||     .....||:|| :|.| ::...:.:                  ..:|..
Zfish   654 KKVIEPMACDGL-----RTICIAYRELPADPLPDWDNETDI------------------VSNLTC 695

  Fly   361 LGMIATYNPPRSTIPKAVDRCRAAGIKLIVVTQRKPKMAKALAVDVGILPAPSDTFQAVNLKRMP 425
            :.::...:|.|..:|.|:.:|:.|||.:.:||......|:|:|...||: .|.|.|..:..|
Zfish   696 ITVVGIEDPVRPEVPDAIRKCQRAGITVRMVTGDNINTARAIAAKCGII-HPGDDFLCMEGK--- 756

  Fly   426 PTAEVVDMS-QYADEKPQHQRRHIEQLILNQQDLVCAATSTDQ---LHWIADAC---RRLGAVVS 483
                  |.: :..:||.:.::..|:: |..:..::..::.||:   :..|.|:.   :|  .||:
Zfish   757 ------DFNRRIRNEKGEIEQERIDK-IWPKLRVLARSSPTDKHTLVKGIIDSTVVEQR--QVVA 812

  Fly   484 VIGGTLHDTPAMRSSHVGVAK--YGSAVMCEASADLILLDTSFATLVSVVGDSRLLFENLKKALA 546
            |.|...:|.||::.:.||.|.  .|:.|..||| |:||.|.:|:::|..|...|.:::::.|.|.
Zfish   813 VTGDGTNDGPALKKADVGFAMGIAGTDVAKEAS-DIILTDDNFSSIVKAVMWGRNVYDSISKFLQ 876

  Fly   547 YCLATNICNILVYLFFFLLGIPLYIHIMDELILAFLVNLVPALTLIYEPPEENLMLQMPKVYDDF 611
            :.|..|:..::|......:.....:..:..|.:..:::...:|.|..|||.|.|:|:.|     :
Zfish   877 FQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTEALLLRKP-----Y 936

  Fly   612 LLNSRLFFVSHILVGTIEAAAVFMTYFVF 640
            ..|:.|  :|..::..|...||:....:|
Zfish   937 GRNNPL--ISRTMMKNILGHAVYQLVIIF 963

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG45062	NP_001286726.1	ATPase-IIC_X-K	<13..794	CDD:273445	166/679 (24%)
atp2b3a	XP_005166875.1	ATPase-IIB_Ca	23..1082	CDD:273668	166/679 (24%)
		ATP_Ca_trans_C	1122..1197	CDD:463575