Protein Alignment CG45062 and atp1a1

DIOPT Version :10

• Sequence 1: NP_001286726.1
• Gene: CG45062 / 19835139
• FlyBaseID: FBgn0266432
• Length: 794
• Species: Drosophila melanogaster
• Sequence 2: NP_989407.1
• Gene: atp1a1 / 395044
• XenbaseID: XB-GENE-484831
• Length: 1023
• Species: Xenopus tropicalis
• Alignment Length: 826
• Identity: 259/826 - (31%)
• Similarity: 420/826 - (50%)
• Gaps: 87/826 - (10%)

  Fly    13 NMGLACTHAISGIGFAVALACGRNTEVGSMTDLCF-KERSRSRSQKHQKQISYYMLLVAI---VC 73
            |:....|:.:.|....|.:..|..|.:|.:..|.. .|..|:......:...:.:..||:   |.
 Frog   241 NIAFFSTNCVEGTARGVVVNTGDRTVMGRIATLASGLEGGRTPIAIEIEHFIHIITGVAVFLGVS 305

  Fly    74 FILLFL--------TTGFEHGHIVYEVNLSLLIGLTPVYLPFILYWGLRRTRKEMGRKQCHVRNL 130
            |.:|.|        ...|..|.||..|...||..:|..         |..|.|.|.||.|.|:||
 Frog   306 FFILSLILQYTWLEAVIFLIGIIVANVPEGLLATVTVC---------LTLTAKRMARKNCLVKNL 361

  Fly   131 RATCTLGLSTVIVSDLVGTMTKRRMRVSEIFVDMGLLSVDNLD------VSAQSPRFIELIRASV 189
            .|..|||.::.|.||..||:|:.||.|:.::.|..:...|..:      ....||.:..|.|.:.
 Frog   362 EAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTENQSGASFDKSSPTWTALSRVAG 426

  Fly   190 LCNDAVICPGNIGVPKMQKDMYGNILDIALLKFGLMILPSIDLLRHDHEKVANKHYNSEDKVQVT 254
            |||.||...|....|.:::|:.|:..:.||||...:...|:..:|..:.|||...:||.:|.|::
 Frog   427 LCNRAVFQAGQENTPILKRDVAGDASESALLKCIELCCGSVRDMREKNPKVAEIPFNSTNKYQLS 491

  Fly   255 VHRTRDADGHLKLVLLMKGHCEVVIRRCSTFAIRDEELPLDEQLQEIILSLADGLLEAGRHVRAF 319
            ||:..: ....:.:|:|||..|.::.||||..::.:|.||||:|::...:....|...|..|..|
 Frog   492 VHKNAN-PSESRYILVMKGAPERILDRCSTIVLQGKEQPLDEELKDAFQNAYLELGGLGERVLGF 555

  Fly   320 AYKELSDELEFRRFSQVNTGLEGGEYKYRDYLAVDTYSLRFLGMIATYNPPRSTIPKAVDRCRAA 384
            .:..|||: :|....|.:|          :.:...|.:|.|:|:|:..:|||:.:|.||.:||:|
 Frog   556 CHLALSDD-QFPDGFQFDT----------EEVNFPTENLCFVGLISMIDPPRAAVPDAVGKCRSA 609

  Fly   385 GIKLIVVTQRKPKMAKALAVDVGILPAPSDTFQAVNLKRMPPTAEV------------VDMSQYA 437
            |||:|:||...|..|||:|..|||:...::|.:.:..:...|..:|            .|:...|
 Frog   610 GIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVNQVNPRDAKACVIHGSDLKDMA 674

  Fly   438 DEKPQHQRRHIEQLILNQQDLVCAATSTDQLHWIADACRRLGAVVSVIGGTLHDTPAMRSSHVGV 502
            .|:       |:.::.:..::|.|.||..|...|.:.|:|.||:|:|.|..::|:||::.:.:|:
 Frog   675 QEQ-------IDDILKHHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGI 732

  Fly   503 AK--YGSAVMCEASADLILLDTSFATLVSVVGDSRLLFENLKKALAYCLATNICNILVYLFFFLL 565
            |.  .||.|..:| ||:||||.:||::|:.|.:.||:|:||||::||.|.:||..|..:|.|.:.
 Frog   733 AMGIAGSDVSKQA-ADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIVA 796

  Fly   566 GIPLYIHIMDELILAFLVNLVPALTLIYEPPEENLMLQMPK-VYDDFLLNSRLFFVSHILVGTIE 629
            .|||.:..:..|.:....::|||::|.||..|.::|.:.|: ...|.|:|.||..:::..:|.|:
 Frog   797 NIPLPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMIQ 861

  Fly   630 AAAVFMTYFVFMADKGFLPRTLVALNIAWHDDMLDDITDSFGQEWSSEARRQLECQVSSLCLMSL 694
            |...|.||||.:|:.||||.||:.:.:.|.|...:|:.||:||:|:.|.|:.:|....:...:|:
 Frog   862 ALGGFFTYFVILAENGFLPWTLLGIRVNWDDRWNNDVEDSYGQQWTYEQRKIVEFTCHTAFFVSI 926

  Fly   695 AVMQCTNLVLTKTGRANLLAHGFRNWLL--------SLAVLLLICLCVQLCIMDSTVCLR---LE 748
            .|:|..:|::.||.|.::...|.:|.:|        :||..|..|..     ||  |.||   |:
 Frog   927 VVVQWADLIICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPG-----MD--VALRMYPLK 984

  Fly   749 GTNELHFGHFLLTNCPFMILLVFIETTRRYFIRLFPDSWLELATMY 794
            .|       :.....|:.:|:...:..|:..||..|..|:|..|.|
 Frog   985 PT-------WWFCAFPYSLLIFIYDEVRKLIIRRSPGGWVEKETYY 1023

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG45062	NP_001286726.1	ATPase-IIC_X-K	<13..794	CDD:273445	258/824 (31%)
atp1a1	NP_989407.1	ATPase-IIC_X-K	32..1023	CDD:273445	258/824 (31%)