Protein Alignment CG45062 and Atp13a2

DIOPT Version :10

• Sequence 1: NP_001286726.1
• Gene: CG45062 / 19835139
• FlyBaseID: FBgn0266432
• Length: 794
• Species: Drosophila melanogaster
• Sequence 2: NP_001424084.1
• Gene: Atp13a2 / 362645
• RGDID: 1307977
• Length: 1173
• Species: Rattus norvegicus
• Alignment Length: 873
• Identity: 174/873 - (19%)
• Similarity: 296/873 - (33%)
• Gaps: 258/873 - (29%)

  Fly    31 LACG------------RNTEVGSMTDLCFKERSRSRSQKHQKQISYYMLLVAIVCFILLFLTTGF 83
            |.||            |...|.:.|..|..:.....|..|.:.||:..                :
  Rat   369 LFCGTLVLQARAYLGPRVLAVVTRTGFCTAKGGLVSSILHPRPISFKF----------------Y 417

  Fly    84 EHGHIVYEVNLSLLIGLTPVYLPFILYWGLRRTRKEMGRKQCHVRNLRATCTLGLSTVIVSD-LV 147
            .|. :.:...||:|..|..:|...|||      |..:..|:..:|      .|.|.||:|.. |.
  Rat   418 RHS-MKFVAALSVLALLGTIYSIIILY------RNRVPVKEIVIR------ALDLVTVVVPPALP 469

  Fly   148 GTMT------KRRMRVSEIFV------------------DMGLLSVDNLDVSAQSPRFIE----- 183
            ..||      :.|:|...||.                  ..|.|:.|.||:....|...:
  Rat   470 AAMTVCTLYAQSRLRTQGIFCIHPLRINLGGKLRLVCFDKTGTLTEDGLDIMGVVPLKGQMLLPL 534

  Fly   184 -----------LIRASVLCNDAVICPGNIGVPKMQKDMYGNILDIALLKFGLMIL---------P 228
                       |:||.|.|:         .:.::...:.|:.:|:.:::....:|         |
  Rat   535 VPEPCHLPPGPLLRALVTCH---------ALSQLHDTLVGDPMDLKMVESTGWVLEEGSAAGSAP 590

  Fly   229 SIDLLRHDHEKVANKHYNSEDKVQVTVHRTRDADGHLKLV-------------LLMKGHCEVVIR 280
            ...:|..............|....|:|.|.......|:.:             ..:||..|:|..
  Rat   591 ETQVLVVMRPPPRGPQQQEESPEPVSVLRRFPFSSALQRMDVVVTWPGATQPEAYVKGSPELVAS 655

  Fly   281 RCSTFAIRDEELPLDEQLQEIILSLADGLLEAGRHVRAFAYKELSDELEFRRFSQVNTGLEGGEY 345
            .||     .|.:|.|  ..:::.|..    .||..|.|.|.|.|          .....||..:.
  Rat   656 LCS-----PETVPRD--FPQVLQSYT----AAGYRVVALAGKPL----------PTAPSLEAAQQ 699

  Fly   346 KYRDYLAVDTYSLRFLGMIATYNPPRSTIPKAVDRCRAAGIKLIVVTQRKPKMAKALAVDVGIL- 409
            ..||.:..:   |..||::...|..:......:...|..||:.::||....:.|..:|...|::
  Rat   700 LTRDTVEQE---LSLLGLLVMRNLLKPQTTPVIQTLRKTGIRTVMVTGDNLQTAVTVAKACGMVG 761

  Fly   410 -----------------PA-----PSDTFQAVNLKRMPPTAEVVDMSQYADEKPQHQRRHIEQ-- 450
                             ||     |::...|:|..:.|     |..:.|..| |:.|.||:..
  Rat   762 TQEHLAIIHATHPEQGQPAALEFLPTEPSAAMNGAKDP-----VQATDYPVE-PESQSRHLALSG 820

  Fly   451 ---LILNQ-----------QDLVCAATSTDQLHWIADACRRLGAVVSVIGGTLHDTPAMRSSHVG 501
               .:|.:           |..|.|..:.:|...:....:||...|.:.|...:|..|::::.||
  Rat   821 STFAVLQKHFPKLLPKVLVQATVFARMAPEQKTQLVCELQRLQYCVGMCGDGANDCGALKAADVG 885

  Fly   502 VAKYGSAVMCEASADLI----------------------LLDTSFATLVSVVGDSRLLFENLKKA 544
            ::      :.:|.|.::                      .|||||:....:...|  |.:.:...
  Rat   886 IS------LSQAEASVVSPFTSSMASIECVPTVIREGRCSLDTSFSVFKYMALYS--LTQFISVL 942

  Fly   545 LAYCLATNICNILVYLFFFLLGIPLYIHIMDELILAFLVNLVPALTLI-YEPPEENLMLQMPKVY 608
            :.|.:.||:.::.      .|.|.|:|   ...:...:....|||||: ..||  ..:|.:|
  Rat   943 ILYTINTNLGDLQ------FLAIDLFI---TTTVAVLMSRTGPALTLVRARPP--GALLSVP--- 993

  Fly   609 DDFLLNSRLFFVSHILVGTIEAAAVFMTYFVFMADKGFLP--RTLVAL-NIAWHDDMLDDITDSF 670
               :|.|.|..|:  ||..|:...    ||:.:|...|:|  ||:.|. |:..:::.:  |....
  Rat   994 ---VLGSLLLQVA--LVAGIQLGG----YFLVIAQPWFVPLNRTVPAPDNLPNYENTV--IFSLS 1047

  Fly   671 GQEW---------SSEARRQLECQVSSLCLMSLAVMQCTNLVLT------KTGRANLLAHGFRNW 720
            |.::         .:..|:.|...|..|..::|.......|:|.      ..|..|:....|:..
  Rat  1048 GFQYLILAAAVSKGAPFRQPLYTNVPFLVALALLGSVLVGLILVPGLLQGPLGLRNIADSSFKLL 1112

  Fly   721 LLSLAVLLLICLCVQLCIMDSTV--CLR 746
            ||.|.....:...:...::|..:  ||:
  Rat  1113 LLGLVAFNFVGAFMLESVLDQCLPACLQ 1140

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG45062	NP_001286726.1	ATPase-IIC_X-K	<13..794	CDD:273445	174/873 (20%)
Atp13a2	NP_001424084.1	None