Protein Alignment CG45062 and ATP7

DIOPT Version :10

• Sequence 1: NP_001286726.1
• Gene: CG45062 / 19835139
• FlyBaseID: FBgn0266432
• Length: 794
• Species: Drosophila melanogaster
• Sequence 2: NP_572756.3
• Gene: ATP7 / 32142
• FlyBaseID: FBgn0030343
• Length: 1254
• Species: Drosophila melanogaster
• Alignment Length: 619
• Identity: 115/619 - (18%)
• Similarity: 215/619 - (34%)
• Gaps: 182/619 - (29%)

  Fly    23 SGIGFAVALACGRNTEVGSMTDLCFKERSRSRS---QKHQKQISYYMLLVAIVCFILL--FLTTG 82
            :|:....|...|.||.:..:..| .:|...|::   |...:...|::..|.:|..|.|  ::..|
  Fly   600 NGVLLVEATHTGENTTLAQIVRL-VEEAQTSKAPIQQLADRIAGYFVPFVVVVSSITLIAWIIIG 663

  Fly    83 FEHGHIVYEVNLSLLIGLTPVYLPFILYWGLRRTRKEMGRKQC--HVRNLRATCTLGLST----- 140
            |.:.::|            ||.:...::............| |  .|..:...|.|||:|
  Fly   664 FSNPNLV------------PVAMEHKMHMDQNTIIVSYAFK-CALSVLAIACPCALGLATPTAVM 715

  Fly   141 --------------------------VIVSDLVGTMTKRRMRVSEIFVDMGLLSVDNLDVSAQ-- 177
                                      .:|.|..||:|......|::          .|.|:||
  Fly   716 VATGTGAINGVLVKGATALENAHKVKTVVFDKTGTITHGTPMTSKV----------TLFVTAQVC 770

  Fly   178 -SPRFIELIRASVLCNDAVICPGNIGVPKMQKDMYGNILDIALL----KFG----LMILP--SID 231
             ..|.:.::.|:...::..|..   .:....|||    |::...    .||    ...:|  .|.
  Fly   771 SLARALTIVGAAEQNSEHPIAS---AIVHFAKDM----LNVGATPQAGSFGKSSHFQAVPGCGIR 828

  Fly   232 LLRHDHEKVANKHYNSEDKVQV-TVHRTR-------DADGHLKLVLLMKGHCEVVIRRCSTFAIR 288
            :...::|:...:..|::..:.. .:|||.       |....::.:|..:.     :|       :
  Fly   829 VTVSNYEQTLRQACNADRIINYENLHRTHPQGSVPVDNGASIEHLLPQRS-----VR-------K 881

  Fly   289 DEELPLDEQLQEIILSLADGLLEAGRHVRAFAYKELSDELEFRRFSQVNTGLEGGEYKYRDYLAV 353
            ..||...:.|.:::|...:.||...:.:.:.....|....|:...:.:...||..:....:....
  Fly   882 SMELNNQQLLSDLVLEPEEELLTDQKIIDSPEILVLIGNREWMERNAIEVPLEISDCMTHEERKG 946

  Fly   354 DTYSL-----RFLGMIATYNPPRSTIPKAVDRCRAAGIKLIVVTQRKPKMAKALAVDVGILPAPS 413
            .|..|     :.:.|.|..:..:.....||...:..||.::::|......|.::|.:|||
  Fly   947 HTAVLCALNGQLVCMFAVSDMVKPEAHLAVYTLKRMGIDVVLLTGDNKNTAASIAREVGI----- 1006

  Fly   414 DTFQAVNLKRMPPTAEVVDMSQYADEKPQHQRRHIEQLILNQQDLVCAATSTDQLHWIADACRRL 478
                               .:.||:..|.|:...|:::..|
  Fly  1007 -------------------RTVYAEVLPSHKVAKIQRIQAN------------------------ 1028

  Fly   479 GAVVSVIGGTLHDTPAMRSSHVGVA-KYGSAVMCEASADLILLDTSFATLVSVVGDSRLLFENLK 542
            |..|:::|..::|:||:..:.||:. ..|:.|..||| |::|:......:|:
  Fly  1029 GIRVAMVGDGVNDSPALAQADVGITIAAGTDVAAEAS-DIVLMRNDLLDVVA------------- 1079

  Fly   543 KALAYCLATNICNI--LVYLFFF-----LLGIPL 569
                 ||..:.|.:  :.|.|||     ||||||
  Fly  1080 -----CLDLSRCTVRRIRYNFFFASMYNLLGIPL 1108

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG45062	NP_001286726.1	ATPase-IIC_X-K	<13..794	CDD:273445	115/619 (19%)
ATP7	NP_572756.3	CopZ	11..76	CDD:442020
		HMA	97..159	CDD:238219
		chaper_CopZ_Eh	212..276	CDD:411374
		HMA	287..350	CDD:238219
		P-type_ATPase_Cu-like	376..1130	CDD:319783	115/619 (19%)