Protein Alignment CG45062 and Atp13a5

DIOPT Version :10

• Sequence 1: NP_001286726.1
• Gene: CG45062 / 19835139
• FlyBaseID: FBgn0266432
• Length: 794
• Species: Drosophila melanogaster
• Sequence 2: NP_783581.2
• Gene: Atp13a5 / 268878
• MGIID: 2444068
• Length: 1216
• Species: Mus musculus
• Alignment Length: 700
• Identity: 142/700 - (20%)
• Similarity: 249/700 - (35%)
• Gaps: 190/700 - (27%)

  Fly    24 GIGFAVALACGRNTEVGSMTDLCFKERSRSRSQKHQKQISY--------YMLLVAIVCFILLFLT 80
            |:..||.|..|.||..|.:.          ||..:.:.:::        :|:.:|.|..:..|..
Mouse   362 GLVRAVVLQTGYNTAKGDLV----------RSILYPRPLNFKLYNDAFKFMVFLACVGVVGFFYA 416

  Fly    81 TGFEHGHIVYEV--------NLSLLIGLTPVYLPFILYWGLRRTRKEMGRKQCHVRNLRATCTLG 137
            .|.   ::.:||        .|.||....|..||..|..|....:|.:.:::....:.:.....|
Mouse   417 LGV---YMYHEVPPRETATMALILLSATVPPVLPAALTIGNVYAQKRLKKEKIFCISPQRINMCG 478

  Fly   138 LSTVIVSDLVGTMTKRRMRVSEIFVDMGLLSVDNLDV------------------SAQSPRFIEL 184
            ...::..|..||:|:                 |.||:                  |.::..:..|
Mouse   479 QINLVCFDKTGTLTE-----------------DGLDLWGTVPTAGNCFQAVHSFASGEAVPWGPL 526

  Fly   185 IRASVLCNDAVICPGNI-GVP---KMQKDMYGNILD--IALLKFGL-----MILP---------- 228
            ..|...|:..::..|.| |.|   ||.:....|:.|  :|..|||:     :|.|
Mouse   527 CAAMTSCHSLILLDGTIQGDPLDLKMFEGTGWNMEDSQVASCKFGMADSSTVIKPGPKASQSPVD 591

  Fly   229 SIDLLRHDHEKVANKHYNSEDKVQVTVHRTRDADGHLKLVLLMKGHCEVVIRRCSTFAIRDEELP 293
            ||.:||        :...|....:::|  .....|.|.|.:.|||..|:|.|.|     |.|.:|
Mouse   592 SITILR--------QFPFSSGLQRMSV--IAQLAGDLHLHVYMKGAPEMVARFC-----RSETVP 641

  Fly   294 --LDEQLQEIILSLADGLLEAGRHVRAFAYKELSDELEFRRFSQVNTGLEGGEYKYRDYLAVDTY 356
              ..::|:...:.        |..|.|.|:|.|..|    |.|.:            |:||.:..
Mouse   642 KNFSQELRNYTVQ--------GFRVIALAHKTLKME----RLSDM------------DHLAREKV 682

  Fly   357 --SLRFLGMIATYNPPRSTIPKAVDRCRAAGIKLIVVTQRKPKMAKALAVDVGILPAPSDTFQAV 419
              .|.|||::...|..:......:.....|.|:.::||....:.|..:|.:..::|..|   |.|
Mouse   683 ESELAFLGLLIMENRLKKETRPVLKELSEARIRTVMVTGDNLQTAITVAKNSEMIPVGS---QVV 744

  Fly   420 NLKRMPP--------TAEVVDMSQ--------YAD----EKPQHQRRH----------------- 447
            .::...|        |.::|...:        |.|    ..|..:..|
Mouse   745 IVEANEPGDLVPASVTWQLVGTQEPGSGKKDTYIDIGNSSVPAGKGYHFAMSGKSYQVLFHHFYS 809

  Fly   448 -IEQLILNQQDLVCAATSTDQLHWIADACRRLGAVVSVIGGTLHDTPAMRSSHVGVAKYGSAVMC 511
             :.|:::|  ..:.|..|..|...:.:..::|...|.:.|...:|..|::.:|.|::      :.
Mouse   810 MLPQILVN--GTIFARMSPGQKSSLVEEFQKLNYYVGMCGDGANDCGALKMAHAGIS------LS 866

  Fly   512 EASADLILLDTSFATLVSVV------GDSRLL--FENLKKALAYCLATNICNILVYLFFFLLGIP 568
            |..|.:....||....:..|      |.:.|:  |...|....|.:...|...|:|....|.|
Mouse   867 EQEASVASPFTSKTANIECVPHLIREGRAALVSSFGVFKYLTMYGIIQFIGTSLLYWQLQLFG-- 929

  Fly   569 LYIHIMDELILAFLVNLVPALTLIY---EPPEENLMLQMPKVYDDFLLNS 615
            .|.:::.::.:..:|:|..::...|   .|......|..|::.....:||
Mouse   930 NYQYLLQDVAITLMVSLTMSINHAYPKLAPYRPAGQLLSPQLLLSVFMNS 979

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG45062	NP_001286726.1	ATPase-IIC_X-K	<13..794	CDD:273445	141/699 (20%)
Atp13a5	NP_783581.2	P5-ATPase	23..142	CDD:463565
		P-type_ATPase_cation	174..999	CDD:319842	141/699 (20%)