Protein Alignment CG45062 and atp1a1a.5

DIOPT Version :10

• Sequence 1: NP_001286726.1
• Gene: CG45062 / 19835139
• FlyBaseID: FBgn0266432
• Length: 794
• Species: Drosophila melanogaster
• Sequence 2: NP_835200.1
• Gene: atp1a1a.5 / 245703
• ZFINID: ZDB-GENE-020501-1
• Length: 1023
• Species: Danio rerio
• Alignment Length: 838
• Identity: 259/838 - (30%)
• Similarity: 429/838 - (51%)
• Gaps: 89/838 - (10%)

  Fly     1 MSSKTLSKWSSSNMGLACTHAISGIGFAVALACGRNTEVGSMTDLCFKERSRSRSQKHQ----KQ 61
            |||:  :...:.|:....|:.|.|....:.:..|..|.:|.:..|.      |..:..|    ::
Zfish   231 MSSE--NPLETRNIAFFSTNCIDGAARGIVVNTGDRTVMGRIASLA------SNLEGGQTPLGRE 287

  Fly    62 ISYYMLLVAIVCFILLFLTTGFEHGHIVYEVNLS--------LLIGL----TPVYLPFILYWGLR 114
            |.::   :.|:..:.:||.|.|    ::..|.|.        .||||    .|..||..:...|.
Zfish   288 IEHF---IHIITGVAVFLGTTF----LIISVMLGFTWLEGIIFLIGLIVANVPEGLPCTVTVALT 345

  Fly   115 RTRKEMGRKQCHVRNLRATCTLGLSTVIVSDLVGTMTKRRMRVSEIFVDMGLLSVDNLD------ 173
            .|.|.|.:|.|.|:||.|..|||.::.|.||..||:|:.||.|:.::.|..:...|..:
Zfish   346 LTAKHMAKKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHIADTTENQTGAS 410

  Fly   174 VSAQSPRFIELIRASVLCNDAVICPGNIGVPKMQKDMYGNILDIALLKFGLMILPSIDLLRHDHE 238
            ....|..:..|.|.:.|||.||.......:|.::::..|:..:.||||...:...|:..:|.::.
Zfish   411 FDRSSATWSALARVAGLCNRAVFQSNQSHLPVLRRETAGDASESALLKCIELCCGSVTGMRENYP 475

  Fly   239 KVANKHYNSEDKVQVTVHRTRDADGHLKLVLLMKGHCEVVIRRCSTFAIRDEELPLDEQLQEIIL 303
            |||...:||..|.|:::|...:: ...|.:|:|||..|.::.||||..|..:|.|||::::|...
Zfish   476 KVAEIPFNSISKYQLSIHENPNS-SEPKHLLVMKGAPERILDRCSTILIEGKEHPLDDEMKEDFQ 539

  Fly   304 SLADGLLEAGRHVRAFAYKELSDELEFRRFSQVNTGLEGGEYKYRDYLAVDTYSLRFLGMIATYN 368
            :....|...|..|..|.:..|.|:    :|.      ||..:...: :...|.:|.|:|:::..:
Zfish   540 NAYVQLGGLGERVLGFCHFCLPDD----QFP------EGFAFDTEE-MNFPTENLCFVGLMSMID 593

  Fly   369 PPRSTIPKAVDRCRAAGIKLIVVTQRKPKMAKALAVDVGILPAPSDTFQ------AVNLKRMPP- 426
            |||:.:|.||.:||:||||:|:||...|..|||:|..|||:...::|..      .:::..:.|
Zfish   594 PPRAAVPDAVAKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVDDIAARLKIHIDEVNPR 658

  Fly   427 --TAEVV---DMSQYADEKPQHQRRHIEQLILNQQDLVCAATSTDQLHWIADACRRLGAVVSVIG 486
              .|.|:   ::....||:       ::.::.:..::|.|.||..|...|.:.|:|.||:|:|.|
Zfish   659 DAKACVIHGGELKNMTDEQ-------LDDVLQHHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTG 716

  Fly   487 GTLHDTPAMRSSHVGVAK--YGSAVMCEASADLILLDTSFATLVSVVGDSRLLFENLKKALAYCL 549
            ..::|:||::.:.:|||.  .||.|..:| ||:||||.:||::|:.|.:.||:|:||||::.|.|
Zfish   717 DGVNDSPALKKADIGVAMGIAGSDVSKQA-ADMILLDDNFASIVTGVEEGRLIFDNLKKSICYTL 780

  Fly   550 ATNICNILVYLFFFLLGIPLYIHIMDELILAFLVNLVPALTLIYEPPEENLMLQMPK-VYDDFLL 613
            :|.|..:..:|.|.|.||||.:..:..|.:....::|||::..||..|.::|.:.|: ...|.|:
Zfish   781 STKIPEMSPFLMFVLAGIPLPLGTVTILCIDLGTDMVPAISFAYENAESDIMKRQPRNAATDRLV 845

  Fly   614 NSRLFFVSHILVGTIEAAAVFMTYFVFMADKGFLPRTLVALNIAWHDDMLDDITDSFGQEWSSEA 678
            |.||..||:..:|.:.|...|.||||.:|:.||||..||.|.|.|:|....::.||:||:|:.|.
Zfish   846 NERLVSVSYGQIGVMNAFGGFFTYFVILAENGFLPWDLVGLRIGWNDRYFSEVEDSYGQQWTYEQ 910

  Fly   679 RRQLECQVSSLCLMSLAVMQCTNLVLTKTGRANLLAHGFRNWLLSL------AVLLLICLCVQLC 737
            |:.||....:....|:.:||.|.|::.|:.|.:|...|.:|.:|:.      |:...:..|..
Zfish   911 RKVLEYTCHTAYFTSIVIMQWTTLLVCKSRRLSLAKQGMKNRVLTFSLFEETAIAAFLSYCPG-- 973

  Fly   738 IMDSTVCLRLEGTNEL-HFGHFLLTNCPFMILLVFIETTRRYFIRLFPDSWLELATMY 794
             ||  :.:|:.....: .|..|     |:|||:...:..|::|||..|..|:|..|.|
Zfish   974 -MD--IAVRMYPLKPMWWFCAF-----PYMILIFIYDEVRKHFIRQNPGGWVERETYY 1023

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG45062	NP_001286726.1	ATPase-IIC_X-K	<13..794	CDD:273445	255/824 (31%)
atp1a1a.5	NP_835200.1	ATPase-IIC_X-K	32..1023	CDD:273445	258/836 (31%)