Protein Alignment CG45062 and Atp1a3

DIOPT Version :10

• Sequence 1: NP_001286726.1
• Gene: CG45062 / 19835139
• FlyBaseID: FBgn0266432
• Length: 794
• Species: Drosophila melanogaster
• Sequence 2: XP_017444264.1
• Gene: Atp1a3 / 24213
• RGDID: 2169
• Length: 1026
• Species: Rattus norvegicus
• Alignment Length: 834
• Identity: 258/834 - (30%)
• Similarity: 426/834 - (51%)
• Gaps: 103/834 - (12%)

  Fly    13 NMGLACTHAISGIGFAVALACGRNTEVGSMTDLCFKERSRSRSQKHQK----QISYYMLL---VA 70
            |:....|:.:.|....|.:|.|..|.:|.:..|.      |..:..:.    :|.:::.|   ||
  Rat   244 NITFFSTNCVEGTARGVVVATGDRTVMGRIATLA------SGLEVGKTPIAIEIEHFIQLITGVA 302

  Fly    71 I---VCFILLFLTTG--------FEHGHIVYEVNLSLLIGLTPVYLPFILYWGLRRTRKEMGRKQ 124
            :   |.|.:|.|..|        |..|.||..|...||..:|..         |..|.|.|.||.
  Rat   303 VFLGVSFFILSLILGYTWLEAVIFLIGIIVANVPEGLLATVTVC---------LTLTAKRMARKN 358

  Fly   125 CHVRNLRATCTLGLSTVIVSDLVGTMTKRRMRVSEIFVDMGLLSVDNLD------VSAQSPRFIE 183
            |.|:||.|..|||.::.|.||..||:|:.||.|:.::.|..:...|..:      ....|..::.
  Rat   359 CLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGTSFDKSSHTWVA 423

  Fly   184 LIRASVLCNDAVICPGNIGVPKMQKDMYGNILDIALLKFGLMILPSIDLLRHDHEKVANKHYNSE 248
            |...:.|||.||...|...:|.:::|:.|:..:.||||...:...|:.|:|..::|||...:||.
  Rat   424 LSHIAGLCNRAVFKGGQDNIPVLKRDVAGDASESALLKCIELSSGSVKLMRERNKKVAEIPFNST 488

  Fly   249 DKVQVTVHRTRDADGHLKLVLLMKGHCEVVIRRCSTFAIRDEELPLDEQLQEIILSLADGLLEAG 313
            :|.|:::|.|.|.:.: :.:|:|||..|.::.||:|..::.:|.||||:::|...:....|...|
  Rat   489 NKYQLSIHETEDPNDN-RYLLVMKGAPERILDRCATILLQGKEQPLDEEMKEAFQNAYLELGGLG 552

  Fly   314 RHVRAFAYKELSDELEFRRFS----QVNTGLEGGEYKYRDYLAVDTYSLRFLGMIATYNPPRSTI 374
            ..|..|.:..|.:|...:.|:    .||               ..|.:|.|:|:::..:|||:.:
  Rat   553 ERVLGFCHYYLPEEQFPKGFAFDCDDVN---------------FTTDNLCFVGLMSMIDPPRAAV 602

  Fly   375 PKAVDRCRAAGIKLIVVTQRKPKMAKALAVDVGILPAPSDTFQAVNLKRMPPTAEV--------- 430
            |.||.:||:||||:|:||...|..|||:|..|||:...::|.:.:..:...|.::|
  Rat   603 PDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACV 667

  Fly   431 ---VDMSQYADEKPQHQRRHIEQLILNQQDLVCAATSTDQLHWIADACRRLGAVVSVIGGTLHDT 492
               .|:..:..|:       |::::.|..::|.|.||..|...|.:.|:|.||:|:|.|..::|:
  Rat   668 IHGTDLKDFTSEQ-------IDEILQNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDS 725

  Fly   493 PAMRSSHVGVAK--YGSAVMCEASADLILLDTSFATLVSVVGDSRLLFENLKKALAYCLATNICN 555
            ||::.:.:|||.  .||.|..:| ||:||||.:||::|:.|.:.||:|:||||::||.|.:||..
  Rat   726 PALKKADIGVAMGIAGSDVSKQA-ADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPE 789

  Fly   556 ILVYLFFFLLGIPLYIHIMDELILAFLVNLVPALTLIYEPPEENLMLQMPK-VYDDFLLNSRLFF 619
            |..:|.|.:..|||.:..:..|.:....::|||::|.||..|.::|.:.|: ...|.|:|.||..
  Rat   790 ITPFLLFIMANIPLPLGTITILCIDLGTDMVPAISLAYEAAESDIMKRQPRNPRTDKLVNERLIS 854

  Fly   620 VSHILVGTIEAAAVFMTYFVFMADKGFLPRTLVALNIAWHDDMLDDITDSFGQEWSSEARRQLEC 684
            :::..:|.|:|...|.:|||.:|:.||||..||.:.:.|.|..::|:.||:||:|:.|.|:.:|.
  Rat   855 MAYGQIGMIQALGGFFSYFVILAENGFLPGNLVGIRLNWDDRTVNDLEDSYGQQWTYEQRKVVEF 919

  Fly   685 QVSSLCLMSLAVMQCTNLVLTKTGRANLLAHGFRNWLL--------SLAVLLLICLCVQLCIMDS 741
            ...:...:|:.|:|..:|::.||.|.::...|.:|.:|        :||..|..|..     ||
  Rat   920 TCHTAFFVSIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPG-----MD- 978

  Fly   742 TVCLRLEGTN-ELHFGHFLLTNCPFMILLVFIETTRRYFIRLFPDSWLELATMY 794
             |.||:.... ...|..|     |:..|:...:..|:..:|..|..|:|..|.|
  Rat   979 -VALRMYPLKPSWWFCAF-----PYSFLIFVYDEIRKLILRRNPGGWVEKETYY 1026

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG45062	NP_001286726.1	ATPase-IIC_X-K	<13..794	CDD:273445	257/832 (31%)
Atp1a3	XP_017444264.1	ATPase-IIC_X-K	31..1026	CDD:273445	257/832 (31%)