Protein Alignment CG45062 and Atp13a3

DIOPT Version :10

• Sequence 1: NP_001286726.1
• Gene: CG45062 / 19835139
• FlyBaseID: FBgn0266432
• Length: 794
• Species: Drosophila melanogaster
• Sequence 2: NP_001121568.1
• Gene: Atp13a3 / 224088
• MGIID: 2685387
• Length: 1249
• Species: Mus musculus
• Alignment Length: 725
• Identity: 139/725 - (19%)
• Similarity: 256/725 - (35%)
• Gaps: 213/725 - (29%)

  Fly    28 AVALACGRNTEVGSMTDLCFKERSRSRSQKHQKQISYYMLLVAIVCFILLFLTTGFEHGHIVYEV 92
            |:.:..|.:|..|.:.          ||..:.|...:.:...|.:..:.|.:..|.  |.|...:
Mouse   374 AIVVRTGFSTSKGQLV----------RSILYPKPTDFKLYRDAYLFLLCLVVVAGI--GFIYTII 426

  Fly    93 N---------------LSLLIGLTPVYLPFILYWGL---RRTRKEMGRKQCHVRNLRATCTLGLS 139
            |               |.::....|..||..:..|:   :|..|::|......:.:.....|.|
Mouse   427 NSILNEKEVQEIIIKSLDIITITVPPALPAAMTAGIVYAQRRLKKVGIFCISPQRINICGQLNL- 490

  Fly   140 TVIVSDLVGTMTKRRMRVSEIFVDMGLLSVDNLDV----SAQSPRFIELIRASVLCNDAVI---- 196
              :..|..||:|:                 |.||:    ..::.||  |:....:|::.::
Mouse   491 --VCFDKTGTLTE-----------------DGLDLWGIQRVENTRF--LLPEDNVCSEMLVKSQF 534

  Fly   197 --CPGNI-GVPKMQKDMYGNILDIALLK--------------------FGLMILPSIDLLRHDHE 238
              |.... .:.|::..:.|:.||:.:.:                    ...::.||..|| .:..
Mouse   535 VACMATCHSLTKIEGVLSGDPLDLKMFEAIGWILEEATEEETALHNRIMPTVVRPSKQLL-PEPT 598

  Fly   239 KVANKH-------------------YNSEDKVQVTVHRTRDADGHLKLVLLMKGHCEVVIRRCST 284
            ...|:.                   ::|..:....|.||.   |..::...|||..|||...|
Mouse   599 TAGNQEMELFELPAIYEIGIVRQFPFSSALQRMSVVARTL---GEKRMDAYMKGAPEVVASLC-- 658

  Fly   285 FAIRDEELPLDEQLQEIILSLADGLLEAGRHVRAFAYKELSDELEFRRFSQVNTGLEGGEYKYRD 349
               :.|.:|:|.:      .:.:...:.|..|.|.|:::|..:|.:.:...::          ||
Mouse   659 ---KPETVPVDFE------KVLEDYTKQGFRVIALAHRKLESKLTWHKVQHIS----------RD 704

  Fly   350 YLAVDTYSLRFLGMIATYNPPRSTIPKAVDRCRAAGIKLIVVTQRKPKMAKALAVDVGILPAPSD 414
              |::. ::.|:|:|...|..:...|..::....|.|:.::||......|.::|.|.|:: .|.|
Mouse   705 --AIEN-NMDFMGLIIMQNKLKQETPAVLEDLHKANIRTVMVTGDNMLTAVSVARDCGMI-LPQD 765

  Fly   415 TFQAVNLKRMPP-TAEVVDMS-QYADEKPQ-----------------HQ--------RRHIE--- 449
              :.:..:.:|| ..:|..:: .|.|...|                 |.        |.|..
Mouse   766 --KVIIAEALPPKDGKVAKINWHYTDSLSQCSESSAIDSEAIPIKLAHDSLEDLEVTRYHFAMNG 828

  Fly   450 ---QLILNQ-QDL---------VCAATSTDQLHWIADACRRLGAVVSVIGGTLHDTPAMRSSHVG 501
               .:||.. |||         |.|..:.||...:.:|.:.:...|.:.|...:|..|::.:|.|
Mouse   829 KSFSVILEHFQDLVPKLMLHGTVFARMAPDQKTQLVEALQNVDYFVGMCGDGANDCGALKRAHGG 893

  Fly   502 VAKYGSAVMCEASADLILLDTSFATLVSVVGDSRLLFENLKKALAYCLATNICNILVYLFFFLLG 566
            ::      :.|..|.:....||....:|.|       .||.:.....|.|:.|   |:.|..|..
Mouse   894 IS------LSELEASVASPFTSKTPSISCV-------PNLIREGRAALMTSFC---VFKFMALYS 942

  Fly   567 IPLYIHIMDELILAFLVN--------------LVPALTLIYEPPEENLMLQMPKVYDDFLLNSRL 617
            |..|..:  .|:.:.|.|              ||...|:...|..:.|:.|.|   ...|::..|
Mouse   943 IIQYFSV--TLLYSILSNLGDFQFLFIDLAIILVVVFTMSLNPAWKELVAQRP---PSGLISGAL 1002

  Fly   618 FF--VSHILV 625
            .|  :|.|::
Mouse  1003 LFSVLSQIVI 1012

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG45062	NP_001286726.1	ATPase-IIC_X-K	<13..794	CDD:273445	139/725 (19%)
Atp13a3	NP_001121568.1	P-ATPase-V	14..1142	CDD:273738	139/725 (19%)