Protein Alignment CG45062 and Atp4a

DIOPT Version :10

• Sequence 1: NP_001286726.1
• Gene: CG45062 / 19835139
• FlyBaseID: FBgn0266432
• Length: 794
• Species: Drosophila melanogaster
• Sequence 2: NP_001277556.1
• Gene: Atp4a / 11944
• MGIID: 88113
• Length: 1034
• Species: Mus musculus
• Alignment Length: 836
• Identity: 246/836 - (29%)
• Similarity: 404/836 - (48%)
• Gaps: 94/836 - (11%)

  Fly     7 SKWSSSNMGLACTHAISGIGFAVALACGRNTEVGSMTDLCFKERSRSRSQKHQK-----QISYYM 66
            |...:.|:....|..:.|....:.::.|..|.:|.:..|       :...:::|     :|.:::
Mouse   245 SPLETRNIAFFSTMCLEGTAQGLVVSTGDRTIIGRIASL-------ASGVENEKTPIAIEIEHFV 302

  Fly    67 LLVA--IVCFILLFLTTGFEHGHIVYEVN---LSLLIGLTPVYLPFILYWGLRRTRKEMGRKQCH 126
            .::|  .:.|...|.......|:......   :::::...|..|...:...|..|.|.:..|.|.
Mouse   303 DIIAGLAILFGATFFVVAMCIGYTFLRAMVFFMAIVVAYVPEGLLATVTVCLSLTAKRLASKNCV 367

  Fly   127 VRNLRATCTLGLSTVIVSDLVGTMTKRRMRVSEIFVDMGLLSVDNL-DVSAQ-----SPRFIELI 185
            |:||.|..|||.::||.||..||:|:.||.||.::.|..:.:.|.. |.|.|     |..:..|.
Mouse   368 VKNLEAVETLGSTSVICSDKTGTLTQNRMTVSHLWFDNHIHTADTTEDQSGQTFDQSSETWRALC 432

  Fly   186 RASVLCNDAVICPGNIGVPKMQKDMYGNILDIALLKFGLMILPSIDLLRHDHEKVANKHYNSEDK 250
            |...|||.|....|...||..::.:.|:..:.|||||..:.|.:....|....||....:||.:|
Mouse   433 RVLTLCNRAAFKSGQDAVPVPKRIVIGDASETALLKFSELTLGNAMGYRDRFPKVCEIPFNSINK 497

  Fly   251 VQVTVHRTRDA--DGHLKLVLLMKGHCEVVIRRCSTFAIRDEELPLDEQLQEII----LSLADGL 309
            .|:::|...|.  ..||   |:|||..|.|:.|||:..|:.:|||||||.:|..    |||. ||
Mouse   498 FQLSIHTLEDPRDSRHL---LVMKGAPERVLERCSSILIKGQELPLDEQWREAFQTAYLSLG-GL 558

  Fly   310 LEAGRHVRAFAYKELSDELEFRRFSQVNTGLEGGEYKYRDY---LAVDTYSLR-------FLGMI 364
               |..|..|....|::                     :||   .|.|..::.       |.|::
Mouse   559 ---GERVLGFCQLYLNE---------------------KDYPPGYAFDVEAMNFPSSGLCFAGLV 599

  Fly   365 ATYNPPRSTIPKAVDRCRAAGIKLIVVTQRKPKMAKALAVDVGILPAPSDTFQAVNLK-RMP--- 425
            :..:|||:|:|.||.:||.|||::|:||...|..|||:|..|||:...|:|.:.:..: |||
Mouse   600 SMIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAASVGIISEGSETVEDIAARLRMPVDQ 664

  Fly   426 -----PTAEVVDMSQYADEKPQHQRRHIEQLILNQQDLVCAATSTDQLHWIADACRRLGAVVSVI 485
                 ..|.|::..|..|..|.    .:.:.:....::|.|.||..|...|.::|:||||:|:|.
Mouse   665 VNRKDARACVINGMQLKDMDPS----ELVEALRTHPEMVFARTSPQQKLVIVESCQRLGAIVAVT 725

  Fly   486 GGTLHDTPAMRSSHVGVAK-YGSAVMCEASADLILLDTSFATLVSVVGDSRLLFENLKKALAYCL 549
            |..::|:||::.:.:|||. ...:...:.:||:||||.:||::|:.|...||:|:||||::||.|
Mouse   726 GDGVNDSPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQGRLIFDNLKKSIAYTL 790

  Fly   550 ATNICNILVYLFFFLLGIPLYIHIMDELILAFLVNLVPALTLIYEPPEENLMLQMPK-VYDDFLL 613
            ..||..:..||.:..:.:||.:..:..|.:....::.|:::|.||..|.::|...|: ...|.|:
Mouse   791 TKNIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLAYEKAESDIMHLRPRNPKRDRLV 855

  Fly   614 NSRLFFVSHILVGTIEAAAVFMTYFVFMADKGFLPRTLVALNIAWHDDMLDDITDSFGQEWSSEA 678
            |..|...|:..:|.|::.|.|..||..||.:|:.|...|.|...|.|..|.|:.||:||||:...
Mouse   856 NEPLAAYSYFQIGAIQSFAGFADYFTAMAQEGWFPLLCVGLRPQWEDHHLQDLQDSYGQEWTFGQ 920

  Fly   679 RRQLECQVSSLCLMSLAVMQCTNLVLTKTGRANLLAHG-FRNWLLSLAVLLLICLCVQLCIMDST 742
            |...:....::..:|:.:.|..::::.||.|.::...| |||.:|.:|::..:|:...||.....
Mouse   921 RLYQQYTCYTVFFISIEMCQIADVLIRKTRRLSVFQQGFFRNKILVIAIVFQVCIGCFLCYCPGM 985

  Fly   743 VCLRLEGTNELHF----GHFLLTNCPFMILLVFIETTRRYFIRLFPDSWLELATMY 794
                   .|..:|    ..:.|...||.:|:...:..|:..:|..|.||.:....|
Mouse   986 -------PNIFNFMPIRFQWWLVPMPFGLLIFVYDEIRKLGVRCCPGSWWDQELYY 1034

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG45062	NP_001286726.1	ATPase-IIC_X-K	<13..794	CDD:273445	244/828 (29%)
Atp4a	NP_001277556.1	H-K_ATPase_N	2..>27	CDD:312544
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	14..41
		ATPase-IIC_X-K	42..1034	CDD:273445	245/834 (29%)