Protein Alignment CG45062 and atp2a2

DIOPT Version :10

• Sequence 1: NP_001286726.1
• Gene: CG45062 / 19835139
• FlyBaseID: FBgn0266432
• Length: 794
• Species: Drosophila melanogaster
• Sequence 2: XP_031748548.1
• Gene: atp2a2 / 100489059
• XenbaseID: XB-GENE-1012933
• Length: 1083
• Species: Xenopus tropicalis
• Alignment Length: 901
• Identity: 192/901 - (21%)
• Similarity: 365/901 - (40%)
• Gaps: 226/901 - (25%)

  Fly    13 NMGLACTHAISGIGFAVALACGRNTEVGSMTD-LCFKERSRSRSQKHQKQISYYM-LLVAIVCFI 75
            ||..:.|:..:|....|.:|.|.|||:|.:.| :...|:.|:..|:...:....: .:::::|..
 Frog   206 NMLFSGTNIAAGKAIGVVVATGVNTEIGKIRDEMVATEQERTPLQQKLDEFGEQLSKVISLICIA 270

  Fly    76 LLFLTTG----------FEHGHIVY-EVNLSLLIGLTPVYLPFILYWGLRRTRKEMGRKQCHVRN 129
            :..:..|          :..|.|.| ::.::|.:...|..||.::...|....:.|.:|...||:
 Frog   271 VWIINIGHFNDPVHGGSWIRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRS 335

  Fly   130 LRATCTLGLSTVIVSDLVGTMTKRRMRVSEIFV------DMGLLSVDNLDVSAQSPR-------- 180
            |.:..|||.::||.||..||:|..:|.|..:|:      |...|:..|:..|..:|.
 Frog   336 LPSVETLGCTSVICSDKTGTLTTNQMSVCRMFIVDKVEGDNCFLNEFNITGSTYAPMGEVLKDDK 400

  Fly   181 ---------FIELIRASVLCND---------------------AVICPGNIGVPKMQKDMYGNIL 215
                     .:||.....||||                     |:.|.    |.||      |:.
 Frog   401 LVKCHQYDGLVELATICALCNDSSLDFNEAKGVYEKVGEATETALTCL----VEKM------NVF 455

  Fly   216 DIALLKFGLMILPSIDLLRHDHEKVANKHYN---SEDKVQVTVHRTRDADGHLKL-VLLMKGHCE 276
            |..|.  ||..:...:......:::..|.:.   |.|:..::|:.|.:......: .:.:||..|
 Frog   456 DTDLK--GLSRIERANACNSVIKQLMKKEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPE 518

  Fly   277 VVIRRCSTFAIRDEELPLDEQLQEIILSLADGLLE--AGRH-VRAFAY--------KE---LSDE 327
            .:|.||:...:...::||...:::.|:|:   :.|  .||. :|..|.        ||   |.|.
 Frog   519 GLIDRCTHIRVGSIKVPLTAGIKQKIMSV---IREWGTGRDTLRCLALATHDNPPRKEDMNLEDS 580

  Fly   328 LEFRRFSQVNTGLEGGEYKYRDYLAVDTYSLRFLGMIATYNPPRSTIPKAVDRCRAAGIKLIVVT 392
            ..|..:..                     :|.|:|.:...:|||:.:..:|..||.|||::|::|
 Frog   581 TNFINYET---------------------NLTFVGCVGMLDPPRTEVAASVKMCRQAGIRVIMIT 624

  Fly   393 QRKPKMAKALAVDVGILPAPSD----TFQAVNLKRMPPTAE---VVDMSQYADEKPQHQRRHIEQ 450
            ......|.|:...|||.....|    .|.......:.|.|:   .::...:|..:|.|:.:.:|.
 Frog   625 GDNKGTAVAICRRVGIFREDEDVSERAFTGREFDELSPAAQRDACLNARCFARVEPSHKSKIVEF 689

  Fly   451 LILNQQDLVCAATSTDQLHWIADACRRLGAVVSVIGGTLHDTPAMRSSHVGVAKYGSAVMCEASA 515
            |           .|.|:             :.::.|..::|.||::.:.:|:|......:.:.::
 Frog   690 L-----------QSFDE-------------ITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKTAS 730

  Fly   516 DLILLDTSFATLVSVVGDSRLLFENLKKALAYCLATNICNILVYLFFFLLGIPLYIHIMDELILA 580
            :::|.|.:|:|:|:.|.:.|.::.|:|:.:.|.:::|:..::.......||.|      :.||..
 Frog   731 EMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFP------EALIPV 789

  Fly   581 FL--VNLV----PALTLIYEPPEENLMLQMPKVYDDFLLNSRLFFVSHILVG------TIEAAAV 633
            .|  ||||    ||..|.:.||:.::|.:.|:...:.|::..||| .::.:|      |:.|||
 Frog   790 QLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFF-RYLAIGCYVGAATVGAAA- 852

  Fly   634 FMTYFVFMADKGFLPRTLVALNIAWHDDMLDDITDSFGQEWSSEARRQLECQV------SSLCLM 692
               ::...|:.|  || :....::......::..|..|          :||::      .::.|.
 Frog   853 ---WWFIAAEDG--PR-ITFYQLSHFLQCREENPDFDG----------VECEIFESPYPMTMALS 901

  Fly   693 SLAVMQCTNLVLTKTGRANLL-AHGFRN-WLLSLAVLLLICLCVQLCIMDSTVCLRLEGTNELHF 755
            .|..::..|.:.:.:...:|| ...:.| |||                  .::||.:    .|||
 Frog   902 VLVTIEMCNALNSLSENQSLLRMPPWENVWLL------------------GSICLSM----SLHF 944

  Fly   756 GHFLLTNCP-------------FMIL-----LVFIETTRRYFIRLFPDSWLELATM 793
            ....:...|             .|:|     ::.::.|.:|..|.:..:.:.|.|:
 Frog   945 LILYVEPLPLIFQITPLNLIQWLMVLKISLPVILLDETLKYVARNYLRACVYLETV 1000

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG45062	NP_001286726.1	ATPase-IIC_X-K	<13..794	CDD:273445	192/901 (21%)
atp2a2	XP_031748548.1	P-type_ATPase_SERCA	5..988	CDD:319778	189/887 (21%)