Protein Alignment CG45062 and atp2b1

DIOPT Version :10

• Sequence 1: NP_001286726.1
• Gene: CG45062 / 19835139
• FlyBaseID: FBgn0266432
• Length: 794
• Species: Drosophila melanogaster
• Sequence 2: XP_031753440.1
• Gene: atp2b1 / 100127567
• XenbaseID: XB-GENE-954671
• Length: 1269
• Species: Xenopus tropicalis
• Alignment Length: 899
• Identity: 195/899 - (21%)
• Similarity: 352/899 - (39%)
• Gaps: 223/899 - (24%)

  Fly     4 KTLSKWSSSNMGLACTHAISGIGFAVALACGRNTEVG--------------------------SM 42
            |||.|   ..:.|:.||.:.|.|..|..|.|.|::.|                          ..
 Frog   249 KTLEK---DPLLLSGTHVMEGSGKMVVTAIGVNSQTGIIFTLLGAGENEEEKEKEKEKKDKKNKK 310

  Fly    43 TDLCFKERSRSRSQ---------------------------KHQKQI---------------SYY 65
            .|...:.|:::::|                           |.:|.:               ...
 Frog   311 QDGAIENRNKAKAQDGAAMEMQPLKSEEGADGDDKKKANLPKKEKSVLQGKLTKLAVQIGKAGLV 375

  Fly    66 MLLVAIVCFILLFLTTGF----------------EHGHIVYEVNLSLLIGLTPVYLPFILYWGLR 114
            |..:.::..:|.|:...|                ::....:.:.:::|:...|..||..:...|.
 Frog   376 MSAITVIILVLYFVINTFWVQKRPWLAECTPIYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLA 440

  Fly   115 RTRKEMGRKQCHVRNLRATCTLGLSTVIVSDLVGTMTKRRMRVSEIFV-DMGLLSVDNLDVSAQS 178
            .:.|:|.:....||:|.|..|:|.:|.|.||..||:|..||.|.:.|: :.....|.:.|..:::
 Frog   441 YSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQSFINEKHYRKVPDPDSISEN 505

  Fly   179 PRFIELIRASVLC--NDAVICPGNI-GVPKMQKDMYGNILDIALLKFGLMILPSIDLLRHDHEKV 240
            ...:.|...||.|  ...::.|... |:|:    ..||..:.|||.|   ||.    ::.|::.|
 Frog   506 VLDLLLTGISVNCAYTSKILPPEKEGGLPR----HVGNKTECALLGF---ILD----MKRDYQDV 559

  Fly   241 ANK----------HYNSEDKVQVTVHRTRDADGHLKLVLLMKGHCEVVIRRC-STFAIRDEE--- 291
            .|:          .:||..|...||  .::|||..:  :..||..|:::::| .|..|..|.
 Frog   560 RNEIPEETLFKVYTFNSVRKSMSTV--LKNADGSYR--MYSKGASEIILKKCFKTLGINGEAKIF 620

  Fly   292 LPLDEQLQEIILSLADGLLEAGRHVRAFAYKEL---SDELEFRRFSQVNTGLEGGEYKYRDYLAV 353
            .|.|.  .:::..:.:.:...|......||::.   ..|.::...:.:.||
 Frog   621 RPRDR--DDMVKRVIEPMASEGLRTICLAYRDFPAGEHEPDWENENDILTG-------------- 669

  Fly   354 DTYSLRFLGMIATYNPPRSTIPKAVDRCRAAGIKLIVVTQRKPKMAKALAVDVGILPAPSDTFQA 418
                |..:.::...:|.|..:|.|:.:|:.|||.:.:||......|:|:|...||| .|.:.|..
 Frog   670 ----LTCIAVVGIEDPVRPEVPDAIRKCQRAGITVRMVTGDNINTARAIATKCGIL-HPGEDFLC 729

  Fly   419 VNLKRMPPTAEVVDMSQYADEKPQHQRRHIEQLILNQQDLVCAATSTDQ---LHWIADA--CRRL 478
            |..|..        ..:..:||.:.::..|:: |..:..::..::.||:   :..|.|:  |.:
 Frog   730 VEGKEF--------NRRIRNEKGEIEQERIDK-IWPKLRVLARSSPTDKHTLVKGIIDSTVCEQ- 784

  Fly   479 GAVVSVIGGTLHDTPAMRSSHVGVAK--YGSAVMCEASADLILLDTSFATLVSVVGDSRLLFENL 541
            ..||:|.|...:|.||::.:.||.|.  .|:.|..||| |:||.|.:|:::|..|...|.:::::
 Frog   785 RQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEAS-DIILTDDNFSSIVKAVMWGRNVYDSI 848

  Fly   542 KKALAYCLATNICNILVYLFFFLLGIPLYIHIMDELILAFLVNLVPALTLIYEPPEENLMLQMPK 606
            .|.|.:.|..|:..::|......:.....:..:..|.:..:::...:|.|..|||.|:|:|:.|
 Frog   849 SKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLLRKP- 912

  Fly   607 VYDDFLLNSRLFFVSHILVGTIEAAAVFMTYFVFMADKGFLPRTLVALNIAWHDDMLDDITDSFG 671
                :..|..|  :|..::..|...||:....||         ||:.:.     :.|.|| || |
 Frog   913 ----YGRNKPL--ISRTMMKNILGHAVYQLVVVF---------TLLFVG-----EKLFDI-DS-G 955

  Fly   672 QEWSSEARRQLECQVSSLCLMSLAVMQCTNLVLTKTGRANLLAHGFRNWLLSLAVLLLICLCVQL 736
            :.....|.   ..|..::...:..:||..|.:..:.      .||.||....:...::.|..|.
 Frog   956 RNAPLHAP---PSQHYTIVFNTFVMMQLFNEINARK------IHGERNVFEGIFNNIIFCSIVL- 1010

  Fly   737 CIMDSTVCLRLEGTNELHFGHFLLTNCPFMILLVFIETTRRYF--IRLFPDSWL 788
                        ||              |:|.:|.::...:.|  ..|..|.||
 Frog  1011 ------------GT--------------FIIQIVIVQFGGKPFSCTELTVDQWL 1038

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG45062	NP_001286726.1	ATPase-IIC_X-K	<13..794	CDD:273445	191/890 (21%)
atp2b1	XP_031753440.1	ATPase-IIB_Ca	12..1060	CDD:273668	195/899 (22%)
		ATP_Ca_trans_C	1099..1198	CDD:463575