Protein Alignment CG45062 and atp2b3

DIOPT Version :10

• Sequence 1: NP_001286726.1
• Gene: CG45062 / 19835139
• FlyBaseID: FBgn0266432
• Length: 794
• Species: Drosophila melanogaster
• Sequence 2: XP_012823355.1
• Gene: atp2b3 / 100125191
• XenbaseID: XB-GENE-977575
• Length: 1242
• Species: Xenopus tropicalis
• Alignment Length: 665
• Identity: 159/665 - (23%)
• Similarity: 289/665 - (43%)
• Gaps: 117/665 - (17%)

  Fly    35 RNTEVGSMTDLCFKERSRSRSQKHQKQI---------------SYYMLLVAIVCFILLFLTTGF- 83
            ::.|.|.|.:   :|:.::...|.:|.:               ...|..:.::..:|.|:...|
 Frog   357 KSAEGGEMEE---REKKKASVPKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFVIQTFV 418

  Fly    84 EHGHI-------VYE--------VNLSLLIGLTPVYLPFILYWGLRRTRKEMGRKQCHVRNLRAT 133
            ..|.:       ||.        :.:::|:...|..||..:...|..:.|:|.:....||:|.|.
 Frog   419 VDGKVWLTECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDAC 483

  Fly   134 CTLGLSTVIVSDLVGTMTKRRMRVSEIFVDMGLLSVDNLDVSAQSPRFIELIRASVLCNDA---- 194
            .|:|.:|.|.||..||:|..||.|.:..:. .:.:.|..|.|:.:.:.::|:..::..|.|
 Frog   484 ETMGNATAICSDKTGTLTTNRMTVVQSNIG-DIHNKDKPDPSSINHKILDLLVNAIAINCAYTTK 547

  Fly   195 VICPGNIGVPKMQKDMYGNILDIALLKFGLMILPSIDLLRHD-HEKVANKHY--NSEDKVQVTVH 256
            ::.|...|....|   .||..:.|||.|.|.:.....|:|.. .|:...|.|  ||..|...|:.
 Frog   548 ILPPEKEGALPQQ---VGNKTECALLGFVLDMQRDYQLVRDQIPEETLYKVYTFNSVRKSMSTII 609

  Fly   257 RTRDADGHLKLVLLMKGHCEVVIRRCS----------TFAIRDEELPLDEQLQEIILSLA-DGLL 310
            |.  .:|..:  |..||..|:|:::||          .|..||.|    |.::::|..:| |||
 Frog   610 RL--PNGGFR--LYSKGASEIVLKKCSNILNSAGDLRAFRARDRE----EMVKKVIEPMACDGL- 665

  Fly   311 EAGRHVRAFAYKELSDELEFRRFSQVNTGLEGGEYKYRDYLAVDTYSLRFLGMIATYNPPRSTIP 375
                .....||::.             .|:...|::..:.:..|   |..:|::...:|.|..:|
 Frog   666 ----RTICIAYRDF-------------PGVPEPEWENENEIVCD---LTCIGVVGIEDPVRPEVP 710

  Fly   376 KAVDRCRAAGIKLIVVTQRKPKMAKALAVDVGILPAPSDTFQAVNLKRMPPTAEVVDMSQYADEK 440
            :|:.:|:.|||.:.:||......|:|:|...||: .|.:.|..:..|..             :.:
 Frog   711 EAIRKCQRAGITVRMVTGDNINTARAIAAKCGII-QPGEDFLCLEGKEF-------------NRR 761

  Fly   441 PQHQRRHIEQLILNQ---QDLVCAATSTDQLHWIADAC--RRLG---AVVSVIGGTLHDTPAMRS 497
            .::::..|||..|::   :..|.|.:|....|.:....  ..:|   .||:|.|...:|.||::.
 Frog   762 IRNEKGEIEQERLDKIWPKLRVLARSSPTDKHTLVKGIIDSTIGEQRQVVAVTGDGTNDGPALKK 826

  Fly   498 SHVGVAK--YGSAVMCEASADLILLDTSFATLVSVVGDSRLLFENLKKALAYCLATNICNILVYL 560
            :.||.|.  .|:.|..||| |:||.|.:|:::|..|...|.:::::.|.|.:.|..|:..::|..
 Frog   827 ADVGFAMGLAGTDVAKEAS-DIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAF 890

  Fly   561 FFFLLGIPLYIHIMDELILAFLVNLVPALTLIYEPPEENLMLQMPKVYDDFLLNSRLFFVSHILV 625
            ....:.....:..:..|.:..:::...:|.|..|||.|:|:|:.|     :..|..|  :|..::
 Frog   891 TGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLLRKP-----YGRNKPL--ISRTMM 948

  Fly   626 GTIEAAAVFMTYFVF 640
            ..|...||:....:|
 Frog   949 KNILGHAVYQLIIIF 963

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG45062	NP_001286726.1	ATPase-IIC_X-K	<13..794	CDD:273445	159/665 (24%)
atp2b3	XP_012823355.1	ATPase-IIB_Ca	13..1083	CDD:273668	159/665 (24%)
		ATP_Ca_trans_C	1122..1168	CDD:463575