Protein Alignment CG45062 and atp1a2

DIOPT Version :10

• Sequence 1: NP_001286726.1
• Gene: CG45062 / 19835139
• FlyBaseID: FBgn0266432
• Length: 794
• Species: Drosophila melanogaster
• Sequence 2: NP_001096439.1
• Gene: atp1a2 / 100125050
• XenbaseID: XB-GENE-6034696
• Length: 1020
• Species: Xenopus tropicalis
• Alignment Length: 822
• Identity: 257/822 - (31%)
• Similarity: 416/822 - (50%)
• Gaps: 80/822 - (9%)

  Fly    13 NMGLACTHAISGIGFAVALACGRNTEVGSMTDLCF-KERSRSRSQKHQKQISYYMLLVAI---VC 73
            |:....|:.:.|.|..:.:..|..|.:|.:..|.. .|..|:......:...:.:..||:   |.
 Frog   239 NICFFSTNCVEGTGRGIVINTGDRTVMGRIATLASGLEVGRTPIAMEIEHFIHIITGVAVFLGVS 303

  Fly    74 FILLFLTTGFEH--------GHIVYEVNLSLLIGLTPVYLPFILYWGLRRTRKEMGRKQCHVRNL 130
            |.:|.|..|:..        |.||..|...||..:|..         |..|.|.|.||.|.|:||
 Frog   304 FFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATVTVC---------LTLTAKRMARKNCLVKNL 359

  Fly   131 RATCTLGLSTVIVSDLVGTMTKRRMRVSEIFVDMGLLSVDNLD------VSAQSPRFIELIRASV 189
            .|..|||.::.|.||..||:|:.||.|:.::.|..:...|..:      ...:||.:..|.|.:.
 Frog   360 EAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGTTFDKRSPTWTALSRIAG 424

  Fly   190 LCNDAVICPGNIGVPKMQKDMYGNILDIALLKFGLMILPSIDLLRHDHEKVANKHYNSEDKVQVT 254
            |||.||...|...|...::|..|:..:.||||...:...|:..||..:.|||...:||.:|.|::
 Frog   425 LCNRAVFKVGQEKVAVSKRDTAGDASESALLKCIELSCGSVRKLRDRNPKVAEIPFNSTNKFQLS 489

  Fly   255 VHRTRDA-DGHLKLVLLMKGHCEVVIRRCSTFAIRDEELPLDEQLQEIILSLADGLLEAGRHVRA 318
            :|...|: :|||   |:|||..|.::.||||..:...|.||||::::...:....|...|..|..
 Frog   490 IHEREDSPEGHL---LVMKGAPERILDRCSTIMLHGAEQPLDEEMKDAFQNAYFELGGLGERVLG 551

  Fly   319 FAYKELSDELEFRRFSQVNTGLEGGEYKYRDYLAVDTYSLRFLGMIATYNPPRSTIPKAVDRCRA 383
            |.:..:..: :|:|..:.:|  :...:...|        |.|:|:|:..:|||:.:|.||.:||:
 Frog   552 FCHLYIPAD-KFQRGFKFDT--DEPNFPLTD--------LCFIGLISMIDPPRAAVPDAVGKCRS 605

  Fly   384 AGIKLIVVTQRKPKMAKALAVDVGILPAPSDTFQAVNLKRMPPTAEV------------VDMSQY 436
            ||||:|:||...|..|||:|..|||:...::|.:.:..:...|..:|            .|:...
 Frog   606 AGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIADRLNIPVNQVNPREAKACVVHGSDLKDM 670

  Fly   437 ADEKPQHQRRHIEQLILNQQDLVCAATSTDQLHWIADACRRLGAVVSVIGGTLHDTPAMRSSHVG 501
            ..|:       ::.|:.|..::|.|.||..|...|.:.|:|.||:|:|.|..::|:||::.:.:|
 Frog   671 TSEQ-------LDDLLKNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIG 728

  Fly   502 VAK--YGSAVMCEASADLILLDTSFATLVSVVGDSRLLFENLKKALAYCLATNICNILVYLFFFL 564
            ||.  .||.|..:| ||:||||.:||::|:.|.:.||:|:||||::||.|.:||..|..:|.|.:
 Frog   729 VAMGIAGSDVSKQA-ADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFII 792

  Fly   565 LGIPLYIHIMDELILAFLVNLVPALTLIYEPPEENLMLQMPK-VYDDFLLNSRLFFVSHILVGTI 628
            ..|||.:..:..|.:....::|||::|.||..|.::|.:.|: ...|.|:|.||..:::..:|.|
 Frog   793 ANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNPRTDKLVNERLISMAYGQIGMI 857

  Fly   629 EAAAVFMTYFVFMADKGFLPRTLVALNIAWHDDMLDDITDSFGQEWSSEARRQLECQVSSLCLMS 693
            :|...|.||||.:|:.||||..|:.:.:.|.|...:|:.||:||||:.|.|:.:|....:....|
 Frog   858 QALGGFFTYFVILAENGFLPSRLLGIRLDWDDRSNNDVEDSYGQEWTYEQRKVVEFTCHTAFFAS 922

  Fly   694 LAVMQCTNLVLTKTGRANLLAHGFRNWLLSLAVLLLICLCVQLCI---MDSTVCLR---LEGTNE 752
            :.|:|..:|::.||.|.::...|.:|.:|...:|....|...|..   ||  |.||   |:.|
 Frog   923 IVVVQWADLIICKTRRNSVFQQGMKNKILIFGLLEETALAAFLSYCPGMD--VALRMYPLKVT-- 983

  Fly   753 LHFGHFLLTNCPFMILLVFIETTRRYFIRLFPDSWLELATMY 794
                 :.....|:.:|:...:..|:..:|..|..|:|..:.|
 Frog   984 -----WWFCAFPYSLLIFLYDEVRKLILRRDPGGWVEKESYY 1020

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG45062	NP_001286726.1	ATPase-IIC_X-K	<13..794	CDD:273445	256/820 (31%)
atp1a2	NP_001096439.1	ATPase-IIC_X-K	30..1020	CDD:273445	256/820 (31%)