DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG45071 and CG12768

DIOPT Version :9

Sequence 1:	NP_730024.1	Gene:	CG45071 / 19834908	FlyBaseID:	FBgn0266441	Length:	429	Species:	Drosophila melanogaster
Sequence 2:	NP_001262229.1	Gene:	CG12768 / 40513	FlyBaseID:	FBgn0037206	Length:	429	Species:	Drosophila melanogaster

Alignment Length:	387	Identity:	86/387 - (22%)
Similarity:	146/387 - (37%)	Gaps:	97/387 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 HDIEER---------PAIWN-RNFHCNKAFLEQ--MWDELSGAHKLPKIVLKAKWKGLRDNFRVE 69
            |:||:|         |.:|: |..|..::...:  .|:||.....:....::..:..||:.||.|
  Fly     6 HNIEKRRLIELVRLNPILWDCRLPHYKRSDKRKAIKWNELGRLFNVNGERVQRTFTSLREIFRRE 70

  Fly    70 YKRIPRADNGDFMVDPATFESKWLHYYALLFLTDHMRHRLP----KNEQDQSFYFSQQSEDCEKT 130
            .       |.:.|:....|:|||.:|.|:.||.:.:|.|..    |:....|...:..|.:....
  Fly    71 L-------NHEKMLGTTRFKSKWEYYDAMAFLKEVIRERKSRERIKHGSLDSAPVATGSSNNNNN 128

  Fly   131 VVEPDLTNGLIRRLQDSDEDYDEEEMEADGEASEATME-ETMPTPPAAHQMN------QVSTTPL 188
            .|..:.:|.     ..|....||.:..|..:.:....: :..|.|.::..:.      .:|..|:
  Fly   129 CVSRNSSNN-----NSSSAALDEYQYFAPSDPNNPNNQPQLQPEPKSSLPVTIPSLSLTLSQLPV 188

  Fly   189 ATGALRAQEEAHQHALIKAGLLR--AQLMELEKEA--EDLSRKPPPPQQMTSPV----------- 238
            |     .|::| ||  ::|..|:  ..|..|:|::  ..|:...|.|...|||.
  Fly   189 A-----LQQQA-QH--LQALQLQPDVTLTSLQKQSLPTSLTNATPAPLAQTSPAQVLSSSRSCSS 245

  Fly   239 APSLQVLVEP--PAAHCSPPPMVT------------TTSAQVQQPGSAAVLAPATTTSASSVSSN 289
            :||:.:..||  ||..| |..::|            |...|.:|...|.:..|....|:|
  Fly   246 SPSIYIKDEPCSPAGGC-PEEVMTGNGPEATRKKLATIRPQTKQQLKARLQLPTPKNSSS----- 304

  Fly   290 GAPMGGKRSVSPPPLYNKAHHPLATLAAAHLAAK----DRNED--------FGPTSAVGGNG 339
                   .:.|||.|...|::.|....|..|...    |.::|        .|.:..:|.:|
  Fly   305 -------YATSPPHLIINANNELIDTDAGDLEEDLDDFDEDDDVTGRCSPIVGQSETMGADG 359

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG45071	NP_730024.1	MADF	14..106	CDD:214738	26/100 (26%)
CG45071	NP_730024.1	BESS	384..418	CDD:281011
CG12768	NP_001262229.1	MADF	12..100	CDD:214738	22/94 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910