Protein Alignment sud1 and TPA1

DIOPT Version :10

• Sequence 1: NP_733061.1
• Gene: sud1 / 19834718
• FlyBaseID: FBgn0265189
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_010969.1
• Gene: TPA1 / 856775
• SGDID: S000000851
• Length: 644
• Species: Saccharomyces cerevisiae
• Alignment Length: 657
• Identity: 149/657 - (22%)
• Similarity: 247/657 - (37%)
• Gaps: 195/657 - (29%)

  Fly    14 KDKDEDGRAEQEDSADQVGEPHRKLLRLGDILETNEVLLNEAYQQPELTKWLQTAWTEEKSQGTK 78
            |.|..:.:.|:|.::.|:.            ||.:::   :....|::       |.:....|.|
Yeast     2 KRKTAEVKGEKERNSKQIS------------LEEDKI---KGMFNPKI-------WDKTFQDGLK 44

  Fly    79 ETQTGAQVFSDPFQICLLPGMLEKGQSQALVAEIIQKVQWSRKQMDLYEFYQSADLSNMPA---- 139
            :....:|    |:....:..::.....:|:..||..::.:::|:.|:|...||.||:|:..
Yeast    45 KEIEDSQ----PYNWGTIHELVNDDLLRAVRKEIETEIHFTKKETDIYRVNQSGDLANLSGLDWD 105

  Fly   140 --CRL--LTNFLQVL-RKQVRPWLEKVT---NLKLDYVSASCSMYTCGDYLLVHDDLLKDRQVAF 196
              .||  |....|:| .||.|.:...||   .|.......|.:.||.|.:||.|||::..|:::|
Yeast   106 DLSRLPNLFKLRQILYSKQYRDFFGYVTKAGKLSGSKTDMSINTYTKGCHLLTHDDVIGSRRISF 170

  Fly   197 IYYLSPWEGAEEWTDEQGGCLEIFGSDDQCFPQFPVQRKIAPKDNQFAFFKV-GSRSFHQVGEVT 260
            |.||.  :...:|....||.|.:|.|.....|......|:.|:.||.||||| ...|||.|.||.
Yeast   171 ILYLP--DPDRKWKSHYGGGLRLFPSILPNVPHSDPSAKLVPQFNQIAFFKVLPGFSFHDVEEVK 233

  Fly   261 TFDYPRLTINGWFH----GD------TNEAFVADSLRA-------------FPR-----LNY--- 294
            . |..||:|.||:|    |:      ..||:|.::...             ||:     |::
Yeast   234 V-DKHRLSIQGWYHIPQVGEEGYIPGEEEAWVRNNTSTLAQIESNVLEDFEFPKDERNILSFHEV 297

  Fly   295 ------LQPDG----LNRPP--------------------LGLFLNNVYLKGATRRSIQKRIEEN 329
                  |:.|.    .|.|.                    |..:::..:|.......:||:..||
Yeast   298 KHFEKMLKGDAGAKTDNTPKESMTSVISDSVKLSEAEFTYLSQYISPEHLSSKGIEKLQKQFVEN 362

  Fly   330 SEICLYEFFKREKFELARSQLLA---------DSDTLK--WRRQGPANAHNYEVLDLTTARG--T 381
            |.:.:..|...:|.||.:..:..         .|..:|  |:...|.:...|..:|....|.  |
Yeast   363 SSLQIESFLNDDKSELLKKVIKQKELEQECPYHSKDVKAPWKTAIPPHKARYLYIDGKEYRNFQT 427

  Fly   382 ILELLQLFRSHAM--FDLLRDFTDL--DLAGT------DAE----------------------SP 414
            ..::|:...::.:  |...:|...:  |.:|.      |||                      :.
Yeast   428 EADILEALNNNDLPNFQFTKDAIKIISDASGNSRENNFDAELALIDLAVFHKSTIFKKYLALLTS 492

  Fly   415 TCSVE----LQRWSHG-NYTV-----LGDGLTSEENTLDLVYYLNAAEGAAVIT----------- 458
            .|.|.    ::|:..| ::|:     ..:.|.|..:.:|.|     .||...:|
Yeast   493 LCPVSEQILIRRFRPGMDFTLATKCRFNELLKSNPDIIDAV-----LEGTLCLTPSAGWESGELG 552

  Fly   459 ----YLAPDAEMPTAKAPTDGR---RSDYDD------EEEDDSVLLTITPVDNALNIVYRCEGTT 510
                |:..|.|        |.:   :.|.:|      ::..||||:...|..|..|:|.|.|...
Yeast   553 GYELYMMDDDE--------DNKQYLKEDVEDASVYRADDSGDSVLINDPPAWNTFNLVLRDESVL 609

  Fly   511 KFTKYVS 517
            :|.||||
Yeast   610 EFVKYVS 616

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sud1	NP_733061.1	2OG-FeII_Oxy_4	172..274	CDD:433386	42/102 (41%)
		Ofd1_CTDD	300..536	CDD:402326	62/317 (20%)
TPA1	NP_010969.1	2OG-FeII_Oxy_4	145..246	CDD:433386	42/103 (41%)
		Ofd1_CTDD	333..638	CDD:402326	60/297 (20%)