Protein Alignment Rlim and CG6923

DIOPT Version :10

• Sequence 1: NP_035406.3
• Gene: Rlim / 19820
• MGIID: 1342291
• Length: 600
• Species: Mus musculus
• Sequence 2: NP_001262484.1
• Gene: CG6923 / 41420
• FlyBaseID: FBgn0037944
• Length: 1265
• Species: Drosophila melanogaster
• Alignment Length: 712
• Identity: 154/712 - (21%)
• Similarity: 230/712 - (32%)
• Gaps: 248/712 - (34%)

Mouse    42 DYRLMRDNNLLGTPGESTEEELLRRLQQIKEG--PPPQSPDENRAGESSDDVTNSDSIIDWLNSV 104
            |.:|.||.:    .|...|.|..|..:..:..  |.|:.|:|:|.       |..|....: ...
  Fly   599 DTQLQRDRD----RGRERERERARDREPYRNDTQPNPEDPNEDRR-------TMYDCAYTF-PYA 651

Mouse   105 RQTGNTTRSGQRG--------------------NQSWRAVSRTNPNSGDF-----------RFSL 138
            |:|...|.:...|                    |.|:......:|..|:|           |:.|
  Fly   652 RRTDRRTEANNEGTSAFAFYSGALADRAAISDHNYSYELDQLMDPGPGNFYPPRCSNMDPQRYFL 716

Mouse   139 EINVNRNNGSQTS----------------------ENESEPSTRRLSVENMESSSQRQMENSASE 181
            .||       ::|                      :|.|..:..|....|:.|:.    .:|:||
  Fly   717 PIN-------ESSMWMPGHPAPPPPPPPMPPILLPDNSSTEAYLRHQQRNLTSTP----SSSSSE 770

Mouse   182 SASARPSRAERNSAE-----------AVTEVPTTRAQRRARSRSPEHRRTRARAERSRSP-LQPT 234
            ..|.:.||..|:|..           |:|.:||.                   .|....| |||.
  Fly   771 QTSTQQSRHRRSSPANVYHRYHPYYYAITTLPTV-------------------VESDYPPSLQPH 816

Mouse   235 SEIPRRAPTLEQSSENEPEGSSRTRHHVTLRQQISGPELLGRGLFAASGSRNPSQGTSSSDTGSN 299
               |...|..:.|.    .||||:        .:||  .|.....||:.:  ..|..:.||..|.
  Fly   817 ---PHPHPHFQPSQ----GGSSRS--------SLSG--ALNAAAVAATAA--AVQAQTFSDLLSQ 862

Mouse   300 SESSG-----SGQR-PPTIVLDLQVRRVRPGEYRQRDSI-------ASRTR-------------- 337
            :.:.|     .|.| ||..::..|        ::||.||       ||...
  Fly   863 AHNEGRAAALEGNRTPPHTMVHAQ--------HQQRQSINPPAPGVASNANLAAAVSPPPPLEMY 919

Mouse   338 -SRSQAPN----------NTVTYESERGGFRRTFSRSERAGVRTYVSTIRIPIR--RILNTGLSE 389
             .||..|:          :...| |.|..::....:..:|......:.|..|.|  .|:.|.|:.
  Fly   920 SGRSTIPHCGSPPFSVRRSEAAY-SNRQHYQPQPHQGHQAPQNQMHAHIHPPHRASAIVATSLTP 983

Mouse   390 T-----------TSVAIQTMLRQIMTGFG-ELSYFMYSDSDSEPSASVSSRN------VERVESR 436
            .           ...::|.|.|:.||... :|       |.:.|..:.:.||      ...|.:|
  Fly   984 APPYPVHQNLWYRQQSMQEMHRRHMTPTPIDL-------SSNAPLLTSTLRNGYLHSICSCVHAR 1041

Mouse   437 NGRGSS-------------GGGNSSGSSSSSSPSPSSSGESSESSSEMFEGSSEGGSSGPSRRDG 488
            ||..||             .......|....||:.|.||.||.::..............|..:..
  Fly  1042 NGPVSSLDPAYYPPYDAAPAAAAPPPSPQQQSPATSGSGNSSVAAQASMRHLQLQPQQQPQAQQS 1106

Mouse   489 -------------------RHRAPVTFDESGSLPFLSLAQFFLLNEDDEDQPRGLTKEQID---- 530
                               .|.:|:.. |.|..| |||....|:.....:  ||.|.|.|:
  Fly  1107 PPVMQHMQRQRAIHHHMFHHHYSPLHL-EIGLAP-LSLGSRILIAPSRPN--RGATLETIERNTL 1167

Mouse   531 -----NLAMRSFGENDALKTCSVCITEYTEGNKLRKLPCSHEYHVHCIDRWLSENSTCPICR 587
                 .:...|..:.||.| |::|:..:...|::|:|||.|.:|..|:|:||..|..|||||
  Fly  1168 PHKYRRVRRPSETDEDAEK-CAICLNLFEIENEVRRLPCMHLFHTDCVDQWLVTNKHCPICR 1228

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rlim	NP_035406.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..24
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	49..355		81/410 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	417..497		21/117 (18%)
		RING-H2_RNF12	544..594	CDD:438336	20/44 (45%)
		PDZ-binding. /evidence=ECO:0000255	597..600
CG6923	NP_001262484.1	HRD1	<1155..>1256	CDD:227568	28/75 (37%)
		RING-H2_RNF111-like	1185..1230	CDD:438137	20/45 (44%)