DRSC/TRiP Functional Genomics Resources

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Protein Alignment EIF4A2 and CG7483

DIOPT Version :9

Sequence 1:NP_001958.2 Gene:EIF4A2 / 1974 HGNCID:3284 Length:407 Species:Homo sapiens
Sequence 2:NP_649788.2 Gene:CG7483 / 40987 FlyBaseID:FBgn0037573 Length:399 Species:Drosophila melanogaster


Alignment Length:378 Identity:275/378 - (72%)
Similarity:320/378 - (84%) Gaps:1/378 - (0%)


- Green bases have known domain annotations that are detailed below.


Human    30 EIVDNFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISILQQ 94
            |::..|:.|||||.|||||||||||||||||||:|.|.:||.||||||||||||||||:|||||.
  Fly    23 EVIPTFNAMNLKEELLRGIYAYGFEKPSAIQQRSITPIVKGRDVIAQAQSGTGKTATFSISILQS 87

Human    95 LEIEFKETQALVLAPTRELAQQIQKVILALGDYMGATCHACIGGTNVRNEMQKLQAEAPHIVVGT 159
            |:...:|||.|.|:||||||.|||||||||||.|...||.||||||:..:::||. ...|||.||
  Fly    88 LDTTLRETQVLCLSPTRELAVQIQKVILALGDMMNVQCHVCIGGTNLGEDIRKLD-YGQHIVSGT 151

Human   160 PGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQKLNTSIQVVLLSATMPTDVLEV 224
            |||||||:.||.|..:.|||.|||||||||::|||:|||::::.|..:.||||:|||:|.::||:
  Fly   152 PGRVFDMIKRRVLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEM 216

Human   225 TKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCDLYETLTITQAVIFLNTRRKVDWL 289
            |.|||.||||||||::||||||||||::.|||||||.|||||||:||||||||||.||:||||||
  Fly   217 TSKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWL 281

Human   290 TEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNR 354
            ||||...:||||::||||.|||||.||:|||:|.||||||||:.||||||||||||||||||.||
  Fly   282 TEKMREANFTVSSMHGDMPQKERDEIMKEFRAGQSRVLITTDVWARGIDVQQVSLVINYDLPNNR 346

Human   355 ENYIHRIGRGGRFGRKGVAINFVTEEDKRILRDIETFYNTTVEEMPMNVADLI 407
            |.|||||||.|||||||||||||..:|.|||||||.:|:|.::||||||||||
  Fly   347 ELYIHRIGRSGRFGRKGVAINFVKSDDIRILRDIEQYYSTQIDEMPMNVADLI 399

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
EIF4A2NP_001958.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..22
PTZ00424 21..407 CDD:185609 273/376 (73%)
Q motif 33..61 22/27 (81%)
DEAD box 183..186 2/2 (100%)
CG7483NP_649788.2 PTZ00424 4..399 CDD:185609 273/376 (73%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG53631
OrthoDB 1 1.010 - - D321438at33208
OrthoFinder 1 1.000 - - FOG0000304
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X250
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
54.930

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