Protein Alignment EIF4A2 and eif4a2

DIOPT Version :10

• Sequence 1: NP_001958.2
• Gene: EIF4A2 / 1974
• HGNCID: 3284
• Length: 407
• Species: Homo sapiens
• Sequence 2: NP_998616.2
• Gene: eif4a2 / 406760
• ZFINID: ZDB-GENE-040426-2802
• Length: 411
• Species: Danio rerio
• Alignment Length: 411
• Identity: 393/411 - (95%)
• Similarity: 402/411 - (97%)
• Gaps: 4/411 - (0%)

Human     1 MSGGSADYN----REHGGPEGMDPDGVIESNWNEIVDNFDDMNLKESLLRGIYAYGFEKPSAIQQ 61
            ||.||||||    |:|||||||:||||||||||||.||||||||||:||||||||||||||||||
Zfish     1 MSSGSADYNSSRDRDHGGPEGMEPDGVIESNWNEITDNFDDMNLKETLLRGIYAYGFEKPSAIQQ 65

Human    62 RAIIPCIKGYDVIAQAQSGTGKTATFAISILQQLEIEFKETQALVLAPTRELAQQIQKVILALGD 126
            |||||||||||||||||||||||||||||||||||||.|||||||||||||||||||||||||||
Zfish    66 RAIIPCIKGYDVIAQAQSGTGKTATFAISILQQLEIEQKETQALVLAPTRELAQQIQKVILALGD 130

Human   127 YMGATCHACIGGTNVRNEMQKLQAEAPHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSR 191
            ||||:||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Zfish   131 YMGASCHACIGGTNVRNEMQKLQAEAPHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSR 195

Human   192 GFKDQIYEIFQKLNTSIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVER 256
            |||||||||||||:|:|||||||||||.||||||.||||:|:|||||||||||||||||||||||
Zfish   196 GFKDQIYEIFQKLSTNIQVVLLSATMPADVLEVTTKFMREPVRILVKKEELTLEGIKQFYINVER 260

Human   257 EEWKLDTLCDLYETLTITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRS 321
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||:|||||||
Zfish   261 EEWKLDTLCDLYETLTITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDIIMREFRS 325

Human   322 GSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTEEDKRILR 386
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Zfish   326 GSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTEEDKRILR 390

Human   387 DIETFYNTTVEEMPMNVADLI 407
            |||||||||||||||||||||
Zfish   391 DIETFYNTTVEEMPMNVADLI 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EIF4A2	NP_001958.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..22		17/24 (71%)
		DEAD-like_helicase_N	21..407	CDD:475120	374/385 (97%)
		Q motif	33..61		26/27 (96%)
		DEAD box	183..186		2/2 (100%)
eif4a2	NP_998616.2	DEAD-like_helicase_N	25..411	CDD:475120	374/385 (97%)