DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Rgs9 and Axn

DIOPT Version :9

Sequence 1:	NP_035398.2	Gene:	Rgs9 / 19739	MGIID:	1338824	Length:	675	Species:	Mus musculus
Sequence 2:	NP_733336.1	Gene:	Axn / 43565	FlyBaseID:	FBgn0026597	Length:	745	Species:	Drosophila melanogaster

Alignment Length:	281	Identity:	59/281 - (20%)
Similarity:	102/281 - (36%)	Gaps:	67/281 - (23%)

- Green bases have known domain annotations that are detailed below.

Mouse   296 WAFNFSELIRDPKGRQSFQYFLKKEFSGEN--LGFWEACEDLK-YGDQSKVKEKAEEIYK----- 352
            ||...:.|:.|..|.:.|:.::::|....|  |.|:.|||.|| ..|..|:|:....||:
  Fly    51 WARTLNHLLEDRDGVELFKKYVEEEAPAYNDHLNFYFACEGLKQQTDPEKIKQIIGAIYRFLRKS 115

Mouse   353 -LFLAPGARRWINIDGKTMDITVKGLRHPHRYVLDAAQTHIYMLMKKDSYARYLKSPIYKEMLAK 416
             |.::...|..|.......:|.:.    ||  :.|..|.|:.:.::.:.|..:|.|.:|
  Fly   116 QLSISDDLRAQIKAIKTNPEIPLS----PH--IFDPMQRHVEVTIRDNIYPTFLCSEMY------ 168

Mouse   417 AIEPQETTKRSSTLPFMRRHLRSSPSPVILRQLEEEEKAREAANTVDITQPGQHLAPSPHLAVYT 481
                                      .:.::|:..:::...::........|...:....||
  Fly   169 --------------------------ILYIQQMSAQQERCTSSGATGSGSAGSSGSGGSSLA--- 204

Mouse   482 GTCVPPSPSSPFSPSCRSPRKPFASPSRFIRRPSIAICPSPSRVALEGSSGLEPKGEASWSGANS 546
            |.|..|    |.:.|.:........|..||..|..::            || .|.|..|.||:..
  Fly   205 GACALP----PTTASGKQQLPQLVPPGAFINLPVSSV------------SG-PPAGTCSASGSVY 252

Mouse   547 GPSVTENREPSADHSRPQPRA 567
            |||.:.:...|...:...||:
  Fly   253 GPSTSASSSGSISATDTLPRS 273

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rgs9	NP_035398.2	DEP_RGS7-like	22..109	CDD:239897
		GGL	219..280	CDD:128520
		RGS_RGS9	292..412	CDD:188693	33/124 (27%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	524..571		13/44 (30%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	637..662
Axn	NP_733336.1	RGS	55..170	CDD:295367	31/152 (20%)
		Axin_b-cat_bind	494..543	CDD:285982
		DIX	665..739	CDD:279160
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3589
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900