DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rgs16 and Axn

DIOPT Version :9

Sequence 1:	NP_035397.2	Gene:	Rgs16 / 19734	MGIID:	108407	Length:	201	Species:	Mus musculus
Sequence 2:	NP_733336.1	Gene:	Axn / 43565	FlyBaseID:	FBgn0026597	Length:	745	Species:	Drosophila melanogaster

Alignment Length:	176	Identity:	40/176 - (22%)
Similarity:	77/176 - (43%)	Gaps:	22/176 - (12%)

- Green bases have known domain annotations that are detailed below.

Mouse    29 KSELSSDTGGISKFEWASKHNKERSFSEDVLGWRESFDLLLNSKNGVAAFHAFLKTEFS--EENL 91
            :|.:...|.|::        :..::.|...|.|..:.:.||..::||..|..:::.|..  .::|
  Fly    27 ESRVKKMTEGVA--------DTSKNSSPSYLNWARTLNHLLEDRDGVELFKKYVEEEAPAYNDHL 83

Mouse    92 EFWLACEEFKKIRSATKLASRAHHIFDEYIRSEAPKEVNIDHETR---ELTKTNLQ-AATTSCFD 152
            .|:.|||..|:.....|:......|: .::|.   .:::|..:.|   :..|||.: ..:...||
  Fly    84 NFYFACEGLKQQTDPEKIKQIIGAIY-RFLRK---SQLSISDDLRAQIKAIKTNPEIPLSPHIFD 144

Mouse   153 VAQGKTRTLMEKDSYPRFLKSPAY----RDLAAQASATSTSAPSGS 194
            ..|......:..:.||.||.|..|    :.::||....::|..:||
  Fly   145 PMQRHVEVTIRDNIYPTFLCSEMYILYIQQMSAQQERCTSSGATGS 190

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rgs16	NP_035397.2	RGS_RGS16	65..178	CDD:188665	29/122 (24%)
Rgs16	NP_035397.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	181..201		5/14 (36%)
Axn	NP_733336.1	RGS	55..170	CDD:295367	29/118 (25%)
		Axin_b-cat_bind	494..543	CDD:285982
		DIX	665..739	CDD:279160
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3589
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900