Protein Alignment Rdx and Moe

DIOPT Version :10

• Sequence 1: NP_001420679.1
• Gene: Rdx / 19684
• MGIID: 97887
• Length: 604
• Species: Mus musculus
• Sequence 2: NP_727290.1
• Gene: Moe / 31816
• FlyBaseID: FBgn0011661
• Length: 649
• Species: Drosophila melanogaster
• Alignment Length: 649
• Identity: 354/649 - (54%)
• Similarity: 453/649 - (69%)
• Gaps: 89/649 - (13%)

Mouse     3 KPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTVGLREVWFFGLQYVDSKGYSTWLKLNKK--- 64
            |.:||||||||||||||||..|||||||||||||:||||||||||||.||||.|||:||.||
  Fly    22 KTLNVRVTTMDAELEFAIQSTTTGKQLFDQVVKTIGLREVWFFGLQYTDSKGDSTWIKLYKKPES 86

Mouse    65 --------------------------------------------------VTQQDVKKENPLQFK 79
                                                              |..|||||||||||:
  Fly    87 PAIKTIKYLKRVKKYVDKKTADSNGVNHLETSEEDDDADDMTGSMPFSTWVMNQDVKKENPLQFR 151

Mouse    80 FRAKFFPEDVSEELIQEITQRLFFLQVKEAILNDEIYCPPETAVLLASYAVQAKYGDYNKEIHKP 144
            |||||:||||:|||||:||.|||:||||.|||.|||||||||:||||||||||::||:||..|..
  Fly   152 FRAKFYPEDVAEELIQDITLRLFYLQVKNAILTDEIYCPPETSVLLASYAVQARHGDHNKTTHTA 216

Mouse   145 GYLANDRLLPQRVLEQHKLTKEQWEERIQNWHEEHRGMLREDSMMEYLKIAQDLEMYGVNYFEIK 209
            |:|||||||||||::|||::|::||:.|..|.:|||.|||||:|||||||||||||||||||||:
  Fly   217 GFLANDRLLPQRVIDQHKMSKDEWEQSIMTWWQEHRSMLREDAMMEYLKIAQDLEMYGVNYFEIR 281

Mouse   210 NKKGTELWLGVDALGLNIYEHDDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRL 274
            |||||:||||||||||||||.||:|||||||||||||||||::|||:|||||||||||:|:|||:
  Fly   282 NKKGTDLWLGVDALGLNIYEQDDRLTPKIGFPWSEIRNISFSEKKFIIKPIDKKAPDFMFFAPRV 346

Mouse   275 RINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQLERAQLENEKKKREIAEKEKER 339
            ||||||||||||||||||||||||||:||||||||||||:.||.||       :|.::|...:||
  Fly   347 RINKRILALCMGNHELYMRRRKPDTIDVQQMKAQAREEKNAKQQER-------EKLQLALAARER 404

Mouse   340 IEREKEELMERLRQIEEQTVKAQKEL---EEQTRKALELEQERQRAKEEAERLDRERRA----AE 397
            .|::::|..:||:|::|...::|::|   ::..|:..|..::.|.||:|.|...:|.:|    .|
  Fly   405 AEKKQQEYEDRLKQMQEDMERSQRDLLEAQDMIRRLEEQLKQLQAAKDELELRQKELQAMLQRLE 469

Mouse   398 EAKSAIAKQAADQMKNQEQLAAELAEFTAKIALLEEAKKKKEEEATEWQHKAFAAQEDLEKTK-- 460
            |||:   .:|.:::|.:|::.|:..|    :..:::....|:||....|.:.    ||..:.:
  Fly   470 EAKN---MEAVEKLKLEEEIMAKQME----VQRIQDEVNAKDEETKRLQDEV----EDARRKQVI 523

Mouse   461 -EELKTVMSAPPPPPPPPVIPPTENEHDEQDEN---SAEASAELSSEGVMNHRSE--EERVTETQ 519
             .|....:.|....|....:...|||::|:..|   ..:.|.:|.::   .|..:  |:|.|..:
  Fly   524 AAEAAAALLAASTTPQHHHVAEDENENEEELTNGDAGGDVSRDLDTD---EHIKDPIEDRRTLAE 585

Mouse   520 KNERVKKQLQALSSELAQARDETKKTQNDVLHAENVKAGRDKYKTLRQIRQGNTKQRIDEFEAM 583
            :|||:..||:||..:|||:|||||:|.||.:|.|||:.|||||||||:||:||||:|:|:||.|
  Fly   586 RNERLHDQLKALKQDLAQSRDETKETANDKIHRENVRQGRDKYKTLREIRKGNTKRRVDQFENM 649

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rdx	NP_001420679.1	B41	7..206	CDD:214604	158/251 (63%)
		FERM_C_ERM	200..296	CDD:270015	85/95 (89%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	310..333		9/22 (41%)
		ERM_helical	347..456	CDD:466641	29/115 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	376..407		11/34 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	437..530		25/100 (25%)
		ERM_C	507..583	CDD:459932	45/77 (58%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	536..555		12/18 (67%)
Moe	NP_727290.1	B41	26..278	CDD:214604	158/251 (63%)
		FERM_C_ERM	272..368	CDD:270015	85/95 (89%)
		ERM_helical	402..521	CDD:466641	34/129 (26%)
		ERM_C	573..649	CDD:459932	44/75 (59%)