DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment EGR4 and odd

DIOPT Version :9

Sequence 1:	NP_001956.4	Gene:	EGR4 / 1961	HGNCID:	3241	Length:	486	Species:	Homo sapiens
Sequence 2:	NP_722922.1	Gene:	odd / 33583	FlyBaseID:	FBgn0002985	Length:	392	Species:	Drosophila melanogaster

Alignment Length:	155	Identity:	48/155 - (30%)
Similarity:	62/155 - (40%)	Gaps:	31/155 - (20%)

- Green bases have known domain annotations that are detailed below.

Human   313 PLGLRSAAAA----DFPKPLVADIPGSSGVAAPPVPPPPPTPFPQAKARRKGRRGGKCSTRCFCP 373
            |.||.|..||    .|.......:.|:.|.:..|                .|..|..
  Fly   174 PAGLHSLHAAVMGRHFGAMPTLKLGGAGGASGVP----------------SGATGSS-------- 214

Human   374 RPHAKAFACPVESCVRSFARSDELNRHLRIHTGHKPFQCRICLRNFSRSDHLTTHVRTHTGEKPF 438
            || .|.|.|  :.|.|.|.:|..|..|.|.||..:|:.|.||.:.|.|.|||..|...|:.:|||
  Fly   215 RP-KKQFIC--KYCNRQFTKSYNLLIHERTHTDERPYSCDICGKAFRRQDHLRDHRYIHSKDKPF 276

Human   439 ACDVCGRRFARSDEKKRHSKVHLKQ 463
            .|..||:.|.:|.....|...||::
  Fly   277 KCSDCGKGFCQSRTLAVHKVTHLEE 301

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
EGR4	NP_001956.4	Atrophin-1	<74..339	CDD:331285	9/29 (31%)
		C2H2 Zn finger	382..404	CDD:275368	8/21 (38%)
		COG5048	408..>466	CDD:227381	22/56 (39%)
		C2H2 Zn finger	412..432	CDD:275368	9/19 (47%)
		C2H2 Zn finger	440..460	CDD:275368	6/19 (32%)
odd	NP_722922.1	COG5048	<203..334	CDD:227381	39/126 (31%)
		C2H2 Zn finger	222..242	CDD:275368	8/21 (38%)
		zf-H2C2_2	234..259	CDD:290200	10/24 (42%)
		C2H2 Zn finger	250..270	CDD:275368	9/19 (47%)
		zf-H2C2_2	262..285	CDD:290200	10/22 (45%)
		C2H2 Zn finger	278..298	CDD:275368	6/19 (32%)
		zf-C2H2	304..326	CDD:278523
		C2H2 Zn finger	306..326	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2698
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.940