Protein Alignment EGR3 and btd

DIOPT Version :9

• Sequence 1: XP_005273482.1
• Gene: EGR3 / 1960
• HGNCID: 3240
• Length: 442
• Species: Homo sapiens
• Sequence 2: NP_511100.1
• Gene: btd / 31912
• FlyBaseID: FBgn0000233
• Length: 644
• Species: Drosophila melanogaster
• Alignment Length: 469
• Identity: 114/469 - (24%)
• Similarity: 164/469 - (34%)
• Gaps: 135/469 - (28%)

Human    22 LRSEDKASERSGSATREQRAWGASPGRERRGVLERTGPREEAELCAVESESPARSGSETTCSCSY 86
            |..:.:..::.....::|:.....|.:::...|         ...|:.|..|:.|||.:..|...
  Fly    61 LTQQQQQQQQQQQQQQQQQQQQQQPQQQQHDFL---------SAAALLSAPPSLSGSSSGSSSGS 116

Human    87 LP---APPREEQQCFSRARACVCENVMDIGLTNEKPNPELSYSG------SFQPAPGNKTVTYLG 142
            .|   .||                      :..|.|.|:.|.:|      |.|.||.:.:|:
  Fly   117 SPLYGKPP----------------------MKLELPYPQASSTGTASPNSSIQSAPSSASVS--- 156

Human   143 KFAFDSPSNWCQDNIISLMSAGILGVPP---ASGALSTQTSTASMVQPPQGDVEAMYPALPPYSN 204
            ...|.||:........|..:......||   |:|||:...:::|   |......|...|....:.
  Fly   157 PSIFPSPAQSFASISASPSTPTTTLAPPTTAAAGALAGSPTSSS---PSSSAASAAAAAAAAAAA 218

Human   205 CGDLYSEPVSFHDPQGNPGLAYS-PQDYQSAKPALDSNLFPMIPDYNLYHHPNDMGSIPEHKPFQ 268
            ..||.:..|:        ..||. ...|....||  .:.|| ...|...::.|.:|.......|.
  Fly   219 AADLGAAAVA--------SAAYGWNTAYSGLGPA--RSQFP-YAQYASDYYGNAVGMSSSAAWFS 272

Human   269 GMDPIRVNPPPITPLETIKAFKDKQIHPGFG-----------------SLPQ--------PPLTL 308
            ..:  |:..|           ...|.:|||.                 :.|.        ||:..
  Fly   273 HQE--RLYQP-----------WSSQSYPGFNFDDIAFQTQLQRRSVRCTCPNCTNEMSGLPPIVG 324

Human   309 KPIRPRKYPNRPSKTPLHERPHACPAEGCDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSD 373
            ...|.||             .|.|...||:|.:.::..|..|||.|||.:||.|..|.:.|||||
  Fly   325 PDERGRK-------------QHICHIPGCERLYGKASHLKTHLRWHTGERPFLCLTCGKRFSRSD 376

Human   374 HLTTHIRTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQK--------------------EKKA 418
            .|..|.||||..:|:||..|.:||:|||...:|.|.|.|.|                    |||.
  Fly   377 ELQRHGRTHTNYRPYACPICSKKFSRSDHLSKHKKTHFKDKKSKKVLAAEAKEQAAAAIKLEKKE 441

Human   419 EKGGAPSASSAPPV 432
            :|.|.|   ..|||
  Fly   442 KKSGKP---LTPPV 452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EGR3	XP_005273482.1	DUF3446	142..202	CDD:288757	14/62 (23%)
		COG5048	324..>388	CDD:227381	27/63 (43%)
		zf-C2H2	330..354	CDD:278523	9/23 (39%)
		C2H2 Zn finger	332..354	CDD:275368	8/21 (38%)
		zf-H2C2_2	346..371	CDD:290200	12/24 (50%)
		COG5048	358..>431	CDD:227381	35/92 (38%)
		C2H2 Zn finger	362..382	CDD:275368	10/19 (53%)
		zf-H2C2_2	374..399	CDD:290200	12/24 (50%)
		C2H2 Zn finger	390..410	CDD:275368	9/19 (47%)
btd	NP_511100.1	C2H2 Zn finger	338..357	CDD:275368	7/18 (39%)
		zf-H2C2_2	349..374	CDD:290200	12/24 (50%)
		C2H2 Zn finger	365..385	CDD:275368	10/19 (53%)
		zf-H2C2_2	377..402	CDD:290200	12/24 (50%)
		zf-C2H2	391..413	CDD:278523	10/21 (48%)
		C2H2 Zn finger	393..413	CDD:275368	9/19 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	133	1.000	Inparanoid score	I4604
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.960