Protein Alignment EGR2 and Egr2

DIOPT Version :10

• Sequence 1: NP_001397860.1
• Gene: EGR2 / 1959
• HGNCID: 3239
• Length: 489
• Species: Homo sapiens
• Sequence 2: NP_001360912.1
• Gene: Egr2 / 13654
• MGIID: 95296
• Length: 483
• Species: Mus musculus
• Alignment Length: 489
• Identity: 433/489 - (88%)
• Similarity: 450/489 - (92%)
• Gaps: 6/489 - (1%)

Human     1 MRVGLPSEASSCPWSARGPRDPPERRRSGLAHVLSDNIYPVEDLAATSVTIFPNAELGGPFDQMN 65
            ||||||:|||||.||||||||.||||||||||||.|::||||||||:|||||||.||||||||||
Mouse     1 MRVGLPTEASSCLWSARGPRDWPERRRSGLAHVLPDSLYPVEDLAASSVTIFPNGELGGPFDQMN 65

Human    66 GVAGDGMINIDMTGEKRSLDLPYPSSFAPVSAPRNQTFTYMGKFSIDPQYPGASCYPEGIINIVS 130
            |||||||||||||||||.|||||||||||:|||||||||||||||||||||||||||||||||||
Mouse    66 GVAGDGMINIDMTGEKRPLDLPYPSSFAPISAPRNQTFTYMGKFSIDPQYPGASCYPEGIINIVS 130

Human   131 AGILQGVTSPASTTASSSVTSASPNPLATGPLGVCTMSQTQPDLDHLYSPPPPPPPYSGCAGDLY 195
            ||||||||.|||||||||||||||||||||||||||||||||:|||||||||||||||||.||||
Mouse   131 AGILQGVTPPASTTASSSVTSASPNPLATGPLGVCTMSQTQPELDHLYSPPPPPPPYSGCTGDLY 195

Human   196 QDPSAFLSAATTSTSSSLAYPPPPSYPSPKPATDPGLFPMIPDYPGFFPSQCQRDLHGTAGPDRK 260
            ||||||||..:|:::|||||.|||||||||||.||||.||||||||||||.||||.||.||||||
Mouse   196 QDPSAFLSPPSTTSTSSLAYQPPPSYPSPKPAMDPGLIPMIPDYPGFFPSPCQRDPHGAAGPDRK 260

Human   261 PFPCPLDTLRVPPPLTPLSTIRNFTLGGPSAGVTGPGASGGSEGPRLPGSSSAAAAAAAAAAYNP 325
            |||||||:|||||||||||||||||||||.|||||||||||.||||||||.|   ||..|..|||
Mouse   261 PFPCPLDSLRVPPPLTPLSTIRNFTLGGPGAGVTGPGASGGGEGPRLPGSGS---AAVTATPYNP 322

Human   326 HHLPLRPILRPRKYPNRPSKTPVHERPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQCRICMR 390
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   323 HHLPLRPILRPRKYPNRPSKTPVHERPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQCRICMR 387

Human   391 NFSRSDHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIHLRQKERKSSAPSASVPAPSTAS 455
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||||...|.|:||
Mouse   388 NFSRSDHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIHLRQKERKSSAPSAPPSAQSSAS 452

Human   456 CSGGVQPGGTLCSSNSSSLGGGPLAPCSSRTRTP 489
            ..||.|.||:||.:::.   |||||.|:||||||
Mouse   453 GPGGSQAGGSLCGNSAI---GGPLASCTSRTRTP 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EGR2	NP_001397860.1	DUF3446	107..201	CDD:463400	90/93 (97%)
		zf-C2H2	353..377	CDD:395048	23/23 (100%)
		C2H2 Zn finger	355..377	CDD:275368	21/21 (100%)
		COG5048	381..>449	CDD:227381	66/67 (99%)
		C2H2 Zn finger	385..405	CDD:275368	19/19 (100%)
		C2H2 Zn finger	413..433	CDD:275368	19/19 (100%)
Egr2	NP_001360912.1	DUF3446	107..202	CDD:463400	91/94 (97%)
		zf-C2H2	350..374	CDD:395048	23/23 (100%)
		C2H2 Zn finger	352..374	CDD:275368	21/21 (100%)
		COG5048	378..>434	CDD:227381	55/55 (100%)
		C2H2 Zn finger	382..402	CDD:275368	19/19 (100%)
		C2H2 Zn finger	410..430	CDD:275368	19/19 (100%)