Protein Alignment EFNB2 and Ephrin

DIOPT Version :10

• Sequence 1: XP_016875895.1
• Gene: EFNB2 / 1948
• HGNCID: 3227
• Length: 335
• Species: Homo sapiens
• Sequence 2: NP_651927.1
• Gene: Ephrin / 43799
• FlyBaseID: FBgn0040324
• Length: 652
• Species: Drosophila melanogaster
• Alignment Length: 230
• Identity: 68/230 - (29%)
• Similarity: 100/230 - (43%)
• Gaps: 47/230 - (20%)

Human    58 DKLDIICPKVDSKTV-GQYEYYKVYMVDKDQADRCTIKKENTPLLN-CAKPDQDIKFTIKFQEFS 120
            |::.||||..:..|. .:.|.|.:|.|.|.:.:.|.|...:..::. |.||.:.:.|||.|:.|:
  Fly   249 DQVHIICPVYEPGTFENETEKYIIYNVSKVEYETCRITNADPRVIAICDKPQKLMFFTITFRPFT 313

Human   121 PNLWGLEFQKNKDYYIISTSNGSLEGLDNQEGGVCQTRAMKILMKVGQDASSAGSTRNKDPTRRP 185
            |...||||....|||.||||  |.:.|..:.||.|.|..||::.||    ..|....||
  Fly   314 PQPGGLEFLPGNDYYFISTS--SKDDLYRRIGGRCSTNNMKVVFKV----CCAPEDNNK------ 366

Human   186 ELEAGTNGRSST-TSPFVKPNPGSSTDGNSAGHSGNNILGSEVALFAGIASGCIIFIVIIITLVV 249
             ..|.:|.:|.| |...:..|..::.:.:...|..|..:|:.:    ||..|.||
  Fly   367 -TTALSNSKSVTDTGGAINVNIANNDESHVNSHGNNIAIGTNI----GINGGQII---------- 416

Human   250 LLLKYRRRHRKHSPQHTTTLSLSTLATPKRSGNNN 284
                       ..|| :..:.::.|     |||||
  Fly   417 -----------GGPQ-SAGIPINPL-----SGNNN 434

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EFNB2	XP_016875895.1	Ephrin-B_Ectodomain	43..167	CDD:259897	42/110 (38%)
Ephrin	NP_651927.1	Ephrin_ectodomain	217..358	CDD:259861	43/114 (38%)