DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment EEF1G and GstD10

DIOPT Version :9

Sequence 1:	NP_001395.1	Gene:	EEF1G / 1937	HGNCID:	3213	Length:	437	Species:	Homo sapiens
Sequence 2:	NP_001287302.1	Gene:	GstD10 / 59240	FlyBaseID:	FBgn0042206	Length:	210	Species:	Drosophila melanogaster

Alignment Length:	151	Identity:	37/151 - (24%)
Similarity:	69/151 - (45%)	Gaps:	12/151 - (7%)

- Green bases have known domain annotations that are detailed below.

Human    46 TPEFLRKFPAGKVPAFEGDDGFCVFESNAIAYYV-----SNEELRGSTPEAAAQVVQWVSFADSD 105
            |||:|:..|...:|... |.||.::||.||..|:     .:::|.....:..|.:.|.:.|....
  Fly    41 TPEYLKINPQHTIPTLH-DHGFALWESRAIMVYLVEKYGKDDKLFPKDVQKQALINQRLYFDMGT 104

Human   106 IVPPASTWVFPTLGIMHHNKQATENAKEEVRRILGLLDAYLKTRTFLVGERVTLADITVVCTLLW 170
            :....|.:.:|.:.:   .|.|.|...:::......|:.:|:.:|:..|...:||||..:.|:..
  Fly   105 LYKSFSEYYYPQIFL---KKPANEENYKKIEVAFEFLNTFLEGQTYSAGGDYSLADIAFLATVST 166

Human   171 LYKQVLEPSFRQAFPNTNRWF 191
            .  .|....|:: :.|..||:
  Fly   167 F--DVAGFDFKR-YANVARWY 184

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
EEF1G	NP_001395.1	GST_N_EF1Bgamma	4..82	CDD:239342	14/40 (35%)
		GST_C_EF1Bgamma_like	91..213	CDD:198290	22/101 (22%)
		tolA	<212..>278	CDD:236545
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	221..268
		EF1G	277..381	CDD:395522
GstD10	NP_001287302.1	GST_N_Delta_Epsilon	1..75	CDD:239343	14/34 (41%)
		PLN02473	3..196	CDD:166114	37/151 (25%)
		GST_C_Delta_Epsilon	89..205	CDD:198287	22/102 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810