DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment EEF1G and GstD7

DIOPT Version :9

Sequence 1:	NP_001395.1	Gene:	EEF1G / 1937	HGNCID:	3213	Length:	437	Species:	Homo sapiens
Sequence 2:	NP_525114.1	Gene:	GstD7 / 48340	FlyBaseID:	FBgn0010043	Length:	224	Species:	Drosophila melanogaster

Alignment Length:	218	Identity:	58/218 - (26%)
Similarity:	91/218 - (41%)	Gaps:	47/218 - (21%)

- Green bases have known domain annotations that are detailed below.

Human    47 PEFLRKFPAGKVPAFEGDDGFCVFESNAIAYYV------SNEELRGSTPEAAAQVVQWVSFADSD 105
            |||:|..|...:|... |:||.::||.|||.|:      .:..|..:.|:..|.:.|.:.|....
  Fly    44 PEFVRINPQHTIPTLV-DNGFVIWESRAIAVYLVEKYGKPDSPLYPNDPQKRALINQRLYFDMGT 107

Human   106 IVPPASTWVFPTLGIMHHNKQATENAKEEVRRILGLLDAYLKTRTFLVGERVTLADITV---VCT 167
            :....:.:.|.   |....|...:.|.::|....|.|:.:|:.:.|:.|.::|:|||.:   |.|
  Fly   108 LYDALTKYFFL---IFRTGKFGDQEALDKVNSAFGFLNTFLEGQDFVAGSQLTVADIVILATVST 169

Human   168 LLWLYKQVLEPSF-RQAFPNTNRWFLTCINQPQFRAVLGEVKLCEKMAQFDAKKFAETQPKKDTP 231
            :.|.       || ...|||..||..   |.|  :...|..:..|.:.|  .|||.
  Fly   170 VEWF-------SFDLSKFPNVERWLK---NAP--KVTPGWEQNLESLQQ--GKKFL--------- 211

Human   232 RKEKGSREEKQKPQAERKEEKKA 254
                      |..||.:::|.||
  Fly   212 ----------QDLQAAKEKEVKA 224

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
EEF1G	NP_001395.1	GST_N_EF1Bgamma	4..82	CDD:239342	15/40 (38%)
		GST_C_EF1Bgamma_like	91..213	CDD:198290	31/125 (25%)
		tolA	<212..>278	CDD:236545	10/43 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	221..268		7/34 (21%)
		EF1G	277..381	CDD:395522
GstD7	NP_525114.1	GST_N_Delta_Epsilon	4..77	CDD:239343	15/33 (45%)
		GstA	6..188	CDD:223698	44/154 (29%)
		GST_C_Delta_Epsilon	92..206	CDD:198287	31/128 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810