DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment EEF1G and GstD6

DIOPT Version :9

Sequence 1:	NP_001395.1	Gene:	EEF1G / 1937	HGNCID:	3213	Length:	437	Species:	Homo sapiens
Sequence 2:	NP_524915.1	Gene:	GstD6 / 48339	FlyBaseID:	FBgn0010042	Length:	215	Species:	Drosophila melanogaster

Alignment Length:	177	Identity:	36/177 - (20%)
Similarity:	81/177 - (45%)	Gaps:	20/177 - (11%)

- Green bases have known domain annotations that are detailed below.

Human    20 IAAQYSGAQVRVLSAPPHFHFGQTNRTPEFLRKFPAGKVPAFEGDDGFCVFESNAIAYYV----- 79
            :..:::..||..        |......|.|::..|...:|... |:.|.::|:.||..|:
  Fly    22 VGVEFNSIQVNT--------FVGEQLEPWFVKINPQHTIPTLV-DNLFVIWETRAIVVYLVEQYG 77

Human    80 SNEELRGSTPEAAAQVVQWVSFADSDIVPPASTWVFPTLGIMHHNKQATENAKEEVRRILGLLDA 144
            .::.|....|:..|.:.|.:.|....:....:.:.||   ::...|..|:...|::.....||:.
  Fly    78 KDDSLYPKDPQKQALINQRLYFDMGTLYDGIAKYFFP---LLRTGKPGTQENLEKLNAAFDLLNN 139

Human   145 YLKTRTFLVGERVTLADITVVCTLLWLYKQVLEPSFRQAFPNTNRWF 191
            :|..:.::.|.::::|||.::.|:  ...::::...:: |||.:||:
  Fly   140 FLDGQDYVAGNQLSVADIVILATV--STTEMVDFDLKK-FPNVDRWY 183

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
EEF1G	NP_001395.1	GST_N_EF1Bgamma	4..82	CDD:239342	13/66 (20%)
		GST_C_EF1Bgamma_like	91..213	CDD:198290	21/101 (21%)
		tolA	<212..>278	CDD:236545
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	221..268
		EF1G	277..381	CDD:395522
GstD6	NP_524915.1	GST_N_Delta_Epsilon	1..74	CDD:239343	13/60 (22%)
		PLN02395	11..208	CDD:166036	36/177 (20%)
		GST_C_Delta_Epsilon	88..204	CDD:198287	21/102 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810