DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment EEF1G and GstD3

DIOPT Version :9

Sequence 1:	NP_001395.1	Gene:	EEF1G / 1937	HGNCID:	3213	Length:	437	Species:	Homo sapiens
Sequence 2:	NP_788656.1	Gene:	GstD3 / 48336	FlyBaseID:	FBgn0010039	Length:	199	Species:	Drosophila melanogaster

Alignment Length:	229	Identity:	48/229 - (20%)
Similarity:	89/229 - (38%)	Gaps:	74/229 - (32%)

- Green bases have known domain annotations that are detailed below.

Human    47 PEFLRKFPAGKVPAFEGDDGFCVFESNAIAYYV-----SNEELRGSTPEAAAQVVQWVSFADSDI 106
            |:|::..|...:|... |:||.::||.||..|:     .::.|.....:..|.:.|.:.|   |:
  Fly    25 PDFIKINPQHSIPTLV-DNGFTIWESRAILVYLVEKYGKDDALYPKDIQKQAVINQRLYF---DM 85

Human   107 VPPASTWVFPTLGIMHHNKQAT-----ENAKEEVRRILGLLDAYLKTRTFLVGERVTLADITVVC 166
                 ..::|||...::....|     |...::|:.....|:.:|:.:.::.|::.|:|||.::.
  Fly    86 -----ALMYPTLANYYYKAFTTGQFGSEEDYKKVQETFDFLNTFLEGQDYVAGDQYTVADIAILA 145

Human   167 TLLWLYKQVLEPSFR------QAFPNTNRWFLTCINQPQFRAVLGEVKLCEKMAQFDAKKFAETQ 225
            .:         .:|.      ..:||..||:                                ..
  Fly   146 NV---------SNFDVVGFDISKYPNVARWY--------------------------------DH 169

Human   226 PKKDTPRKEK---GSREEKQKPQAERKEEKKAAA 256
            .||.||..|:   |:.:.|     :|.|||:.||
  Fly   170 VKKITPGWEENWAGALDVK-----KRIEEKQNAA 198

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
EEF1G	NP_001395.1	GST_N_EF1Bgamma	4..82	CDD:239342	12/39 (31%)
		GST_C_EF1Bgamma_like	91..213	CDD:198290	22/132 (17%)
		tolA	<212..>278	CDD:236545	13/48 (27%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	221..268		13/39 (33%)
		EF1G	277..381	CDD:395522
GstD3	NP_788656.1	GST_N_Delta_Epsilon	<1..58	CDD:239343	12/33 (36%)
		GstA	6..173	CDD:223698	36/197 (18%)
		GST_C_Delta_Epsilon	72..188	CDD:198287	28/164 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810