DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment EEF1G and GstD9

DIOPT Version :9

Sequence 1:	NP_001395.1	Gene:	EEF1G / 1937	HGNCID:	3213	Length:	437	Species:	Homo sapiens
Sequence 2:	NP_001287303.1	Gene:	GstD9 / 41502	FlyBaseID:	FBgn0038020	Length:	218	Species:	Drosophila melanogaster

Alignment Length:	195	Identity:	45/195 - (23%)
Similarity:	82/195 - (42%)	Gaps:	25/195 - (12%)

- Green bases have known domain annotations that are detailed below.

Human     6 LYTYPENWRAFKALIAAQYSGAQVRV----LSAPPHFHFGQTNRTPEFLRKFPAGKVPAFEGDDG 66
            ||:.|    ....|:.|:..|.::..    |.|..|.       .|||::..|...:|... |||
  Fly     8 LYSAP----CRSILMTARALGLELNKKQVDLDAGEHL-------KPEFVKINPQHTIPTLV-DDG 60

Human    67 FCVFESNAIAYYVSNE-----ELRGSTPEAAAQVVQWVSFADSDIVPPASTWVFPTLGIMHHNKQ 126
            |.::||.||..|::.:     .|....|:..|.:.|.:.|..|.:......:.:|.| .....|.
  Fly    61 FAIWESRAILIYLAEKYDKDGSLYPKDPQQRAVINQRLFFDLSTLYQSYVYYYYPQL-FEDVKKP 124

Human   127 ATENAKEEVRRILGLLDAYLKTRTFLVGERVTLADITVVCTLLWLYKQVLEPSFRQAFPNTNRWF 191
            |..:..:::.....:.:..||.:.:....::||||..::.|:...  ::.|..|.: :|...||:
  Fly   125 ADPDNLKKIDDAFAMFNTLLKGQQYAALNKLTLADFALLATVSTF--EISEYDFGK-YPEVVRWY 186

Human 192 191
Fly 187 186

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
EEF1G	NP_001395.1	GST_N_EF1Bgamma	4..82	CDD:239342	23/79 (29%)
		GST_C_EF1Bgamma_like	91..213	CDD:198290	20/101 (20%)
		tolA	<212..>278	CDD:236545
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	221..268
		EF1G	277..381	CDD:395522
GstD9	NP_001287303.1	GST_N_Delta_Epsilon	2..75	CDD:239343	23/78 (29%)
		GstA	4..187	CDD:223698	45/195 (23%)
		GST_C_Delta_Epsilon	89..207	CDD:198287	20/102 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810