DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment EEF1G and GstE11

DIOPT Version :9

Sequence 1:	NP_001395.1	Gene:	EEF1G / 1937	HGNCID:	3213	Length:	437	Species:	Homo sapiens
Sequence 2:	NP_001286575.1	Gene:	GstE11 / 37128	FlyBaseID:	FBgn0034354	Length:	225	Species:	Drosophila melanogaster

Alignment Length:	232	Identity:	49/232 - (21%)
Similarity:	90/232 - (38%)	Gaps:	41/232 - (17%)

- Green bases have known domain annotations that are detailed below.

Human     6 LYTYPENWRAFKALIAAQYSGAQ--VRVLSAPPHFHFGQTNRTPEFLRKFPAGKVPAFEGDDGFC 68
            ||..|.:......|:.|...|.:  :|:::.....|     ::.|||:......:|..: |:|..
  Fly     7 LYYAPRSPPCRAVLLTAAALGLELDLRLVNVKAGEH-----KSAEFLKLNAQHTIPVLD-DNGTI 65

Human    69 VFESNAIAYYVS-------NEELRGSTPEAAAQVVQWVSFADSDIVPPASTWVFPTLGIMHHNKQ 126
            |.:|:.|..|::       ::.|....||....|...:.:....:.|.....|.|.:..     .
  Fly    66 VSDSHIICSYLADKYAPEGDDSLYPKDPEKRRLVDARLYYDCGHLFPRIRFIVEPVIYF-----G 125

Human   127 ATENAKEEVRRILGLLDAY------LKTRTFLVGERVTLADITVVCTLLWLYKQVLEPSFRQAFP 185
            |.|...:   |:..|..||      |....:|||:::|:||::.:.::  ...:...|.....||
  Fly   126 AGEVPSD---RVAYLQKAYDGLEHCLAEGDYLVGDKLTIADLSCIASV--STAEAFAPIEPDQFP 185

Human   186 NTNRW--------FLTCINQPQFRAVLGEVK--LCEK 212
            ...:|        :....||.....::|.||  |.|:
  Fly   186 RLVQWVKRIQALPYYQKNNQEGLDMLVGLVKGLLAER 222

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
EEF1G	NP_001395.1	GST_N_EF1Bgamma	4..82	CDD:239342	18/84 (21%)
		GST_C_EF1Bgamma_like	91..213	CDD:198290	28/138 (20%)
		tolA	<212..>278	CDD:236545	0/1 (0%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	221..268
		EF1G	277..381	CDD:395522
GstE11	NP_001286575.1	GstA	5..198	CDD:223698	42/206 (20%)
		GST_N_Delta_Epsilon	5..78	CDD:239343	18/76 (24%)
		GST_C_Delta_Epsilon	94..211	CDD:198287	24/126 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810