DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment EEF1G and GstE8

DIOPT Version :9

Sequence 1:	NP_001395.1	Gene:	EEF1G / 1937	HGNCID:	3213	Length:	437	Species:	Homo sapiens
Sequence 2:	NP_001286571.1	Gene:	GstE8 / 37113	FlyBaseID:	FBgn0063492	Length:	222	Species:	Drosophila melanogaster

Alignment Length:	206	Identity:	52/206 - (25%)
Similarity:	93/206 - (45%)	Gaps:	30/206 - (14%)

- Green bases have known domain annotations that are detailed below.

Human    14 RAFKALIAA---QYSGAQVRVLSAPPHFHFGQTNRTPEFLRKFPAGKVPAFEGDDGFCVFESNAI 75
            ||.|..:||   .|...::..|:        :...:||||||.|...||..| |||..:::|:||
  Fly    16 RAAKLTLAALGIPYEYVKINTLA--------KETLSPEFLRKNPQHTVPTLE-DDGHFIWDSHAI 71

Human    76 AYYVSNEELRGST--PEAAAQ---VVQWVSFADSDIVPPASTWVFPTLGI---MHHNKQAT--EN 130
            :.|:.::..:..|  |:...|   |.|.:.| :|.:|     :|....||   :....|.|  :.
  Fly    72 SAYLVSKYGQSDTLYPKDLLQRAVVDQRLHF-ESGVV-----FVNGLRGITKPLFATGQTTIPKE 130

Human   131 AKEEVRRILGLLDAYLKTRTFLVGERVTLADITVVCTLLWLYKQVLEPSFRQAFPNTNRWFLTCI 195
            ..:.|..|...::.:|....|:.|:::|:||.:::.::..|...|:..:.:.|  |...|.....
  Fly   131 RYDAVIEIYDFVETFLTGHDFIAGDQLTIADFSLITSITALAVFVVIDTVKYA--NITAWIKRIE 193

Human   196 NQPQFRAVLGE 206
            ..|.:....|:
  Fly   194 ELPYYEEACGK 204

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
EEF1G	NP_001395.1	GST_N_EF1Bgamma	4..82	CDD:239342	24/70 (34%)
		GST_C_EF1Bgamma_like	91..213	CDD:198290	26/124 (21%)
		tolA	<212..>278	CDD:236545
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	221..268
		EF1G	277..381	CDD:395522
GstE8	NP_001286571.1	GstA	4..196	CDD:223698	50/196 (26%)
		GST_N_Delta_Epsilon	4..77	CDD:239343	24/69 (35%)
		GST_C_Delta_Epsilon	91..209	CDD:198287	26/122 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810