DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment EEF1G and GstE7

DIOPT Version :9

Sequence 1:	NP_001395.1	Gene:	EEF1G / 1937	HGNCID:	3213	Length:	437	Species:	Homo sapiens
Sequence 2:	NP_611329.1	Gene:	GstE7 / 37112	FlyBaseID:	FBgn0063493	Length:	223	Species:	Drosophila melanogaster

Alignment Length:	212	Identity:	53/212 - (25%)
Similarity:	83/212 - (39%)	Gaps:	44/212 - (20%)

- Green bases have known domain annotations that are detailed below.

Human    14 RAFKALIAAQYSGAQVRVLSAPPHFHFGQT----NRTPEFLRKFPAGKVPAFEGDDGFCVFESNA 74
            ||.|..:||         |..|..|....|    |.:.|||:|.|...||..| |||..:::|:|
  Fly    16 RAVKLTLAA---------LEVPYEFVEVNTRAKENFSEEFLKKNPQHTVPTLE-DDGHYIWDSHA 70

Human    75 -IAYYVS----------NEELRGSTPEAAAQVVQWVSFADS--DIVPPASTWVFPTLGIMHHNKQ 126
             |||.||          .:.|:.:..:........|.||::  .|..|           :...||
  Fly    71 IIAYLVSKYGKTDSLYPKDLLQRAVVDQRLHFESGVIFANALRSITKP-----------LFAGKQ 124

Human   127 ATENAKEE---VRRILGLLDAYLKTRTFLVGERVTLADITVVCTLLWLYKQVLEPSFRQAFPNTN 188
             |...||.   :..:...|:.:|....::.|.::|:||.:::.|:..|  :|........:|...
  Fly   125 -TMIPKERYDAIIEVYDFLEKFLAGNDYVAGNQLTIADFSIISTVSSL--EVFVKVDTTKYPRIA 186

Human   189 RWFLTCINQPQFRAVLG 205
            .||......|.:....|
  Fly   187 AWFKRLQKLPYYEEANG 203

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
EEF1G	NP_001395.1	GST_N_EF1Bgamma	4..82	CDD:239342	28/82 (34%)
		GST_C_EF1Bgamma_like	91..213	CDD:198290	24/120 (20%)
		tolA	<212..>278	CDD:236545
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	221..268
		EF1G	277..381	CDD:395522
GstE7	NP_611329.1	GstA	4..196	CDD:223698	51/203 (25%)
		GST_N_Delta_Epsilon	4..77	CDD:239343	26/70 (37%)
		GST_C_Delta_Epsilon	91..209	CDD:198287	25/127 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810