DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment EEF1G and GstE2

DIOPT Version :9

Sequence 1:	NP_001395.1	Gene:	EEF1G / 1937	HGNCID:	3213	Length:	437	Species:	Homo sapiens
Sequence 2:	NP_611324.1	Gene:	GstE2 / 37107	FlyBaseID:	FBgn0063498	Length:	221	Species:	Drosophila melanogaster

Alignment Length:	201	Identity:	55/201 - (27%)
Similarity:	87/201 - (43%)	Gaps:	33/201 - (16%)

- Green bases have known domain annotations that are detailed below.

Human    14 RAFKALIAA---QYSGAQVRVLSAPPHFHFGQTNRTPEFLRKFPAGKVPAFEGDDGFCVFESNAI 75
            ||.|..:.|   .|...::.:| |..||       ...||:|.|...||..| |:|..:::|:||
  Fly    17 RACKLTLRALNLDYEYKEMDLL-AGDHF-------KDAFLKKNPQHTVPLLE-DNGALIWDSHAI 72

Human    76 AYYV-----SNEELRGSTPEAAAQVVQWVSFADSDIVPPASTWVFPTL---GIMHHNKQATENAK 132
            ..|:     :::||........|||.|.: |.|:.|       :|.:|   .|.:..:|.:...|
  Fly    73 VCYLVDKYANSDELYPRDLVLRAQVDQRL-FFDASI-------LFMSLRNVSIPYFLRQVSLVPK 129

Human   133 EEVRRI---LGLLDAYLKTRTFLVGERVTLADITVVCTLLWLYKQVLEPSFRQAFPNTNRWFLTC 194
            |:|..|   .|.|:.:|....:|.|.::|:||:....|...| ..||:.. ...:|....||...
  Fly   130 EKVDNIKDAYGHLENFLGDNPYLTGSQLTIADLCCGATASSL-AAVLDLD-ELKYPKVAAWFERL 192

Human   195 INQPQF 200
            ...|.:
  Fly   193 SKLPHY 198

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
EEF1G	NP_001395.1	GST_N_EF1Bgamma	4..82	CDD:239342	22/75 (29%)
		GST_C_EF1Bgamma_like	91..213	CDD:198290	31/116 (27%)
		tolA	<212..>278	CDD:236545
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	221..268
		EF1G	277..381	CDD:395522
GstE2	NP_611324.1	GstA	5..196	CDD:223698	54/197 (27%)
		GST_N_Delta_Epsilon	5..78	CDD:239343	22/69 (32%)
		GST_C_Delta_Epsilon	94..209	CDD:198287	31/115 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810