DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment EEF1G and GstE10

DIOPT Version :9

Sequence 1:	NP_001395.1	Gene:	EEF1G / 1937	HGNCID:	3213	Length:	437	Species:	Homo sapiens
Sequence 2:	NP_001286570.1	Gene:	GstE10 / 37105	FlyBaseID:	FBgn0063499	Length:	240	Species:	Drosophila melanogaster

Alignment Length:	219	Identity:	53/219 - (24%)
Similarity:	86/219 - (39%)	Gaps:	47/219 - (21%)

- Green bases have known domain annotations that are detailed below.

Human    29 VRVLSAPPHFHF----GQTNRTPEFLRKFPAGKVPAFEGDDGFCVFESNAIAYYVSN-----EEL 84
            :|.|.....||.    ...:..|:.|||.|...||..| |...|:::|:||..|:.|     :||
  Fly    22 LRALQLDHEFHTLDMQAGDHLKPDMLRKNPQHTVPMLE-DGESCIWDSHAIIGYLVNKYAQSDEL 85

Human    85 RGSTPEAAAQVVQWVSFADSDIVPPASTWVFPTLGIMHH-----------NKQATENAKE---EV 135
            ....|...|.|.|.:.|               ..|::.|           .:.|||..|:   |:
  Fly    86 YPKDPLKRAVVDQRLHF---------------ETGVLFHGIFKQLQRALFKENATEVPKDRLAEL 135

Human   136 RRILGLLDAYLKTRTFLVGERVTLADITVVCTLLWLYKQVLEPSFRQAFPNTNRWFLTCINQPQF 200
            :....||:.:|....::.|.::|:||.::|.|:..|:.... |.....:|..:.|.......|.:
  Fly   136 KDAYALLEQFLAENPYVAGPQLTIADFSIVATVSTLHLSYC-PVDATKYPKLSAWLARISALPFY 199

Human   201 RA--VLGEVKLCEKM-----AQFD 217
            ..  :.|...|.:|:     .|||
  Fly   200 EEDNLRGARLLADKIRSKLPKQFD 223

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
EEF1G	NP_001395.1	GST_N_EF1Bgamma	4..82	CDD:239342	19/61 (31%)
		GST_C_EF1Bgamma_like	91..213	CDD:198290	27/137 (20%)
		tolA	<212..>278	CDD:236545	4/11 (36%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	221..268
		EF1G	277..381	CDD:395522
GstE10	NP_001286570.1	GstA	4..197	CDD:223698	46/191 (24%)
		GST_N_Delta_Epsilon	4..77	CDD:239343	18/55 (33%)
		GST_C_Delta_Epsilon	91..211	CDD:198287	26/135 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810