DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment EEF1G and GstE13

DIOPT Version :9

Sequence 1:	NP_001395.1	Gene:	EEF1G / 1937	HGNCID:	3213	Length:	437	Species:	Homo sapiens
Sequence 2:	NP_001188889.1	Gene:	GstE13 / 35928	FlyBaseID:	FBgn0033381	Length:	226	Species:	Drosophila melanogaster

Alignment Length:	255	Identity:	59/255 - (23%)
Similarity:	101/255 - (39%)	Gaps:	67/255 - (26%)

- Green bases have known domain annotations that are detailed below.

Human     1 MAAGTLYTYPENWRAFKALIAAQYSGAQVRVLSAPPHF----HFGQTNRTPEFLRKFPAGKVPAF 61
            |:..|||....:..|...::.|:..|..:.:  .|..|    |..:     ||::..|..::|.|
  Fly     1 MSKPTLYYALFSPPARACILVAKLIGLDLEL--KPVDFAKKEHLSE-----EFVKLNPQHQIPVF 58

Human    62 EGDDGFCVFESNAI-----AYYVSNEELRGSTPEAAAQVVQWVSFAD-------SDIVP------ 108
            ...||....:|:||     |.|..|::|.....:..|.:...:.:.:       .|||.
  Fly    59 VDSDGEVYVDSHAIVCFLVAKYAGNDQLYPRDLKRRAHIDHRMHYENGVLFQVVKDIVARNIYGG 123

Human   109 -----PASTWVFPTLGIMHHNKQATENAKEEVRRILGLLDAYLKTRTFLVGERVTLADITVVCTL 168
                 |.|      |.:.|       ||..:       |:.:|:..:|:||..:::||:::..||
  Fly   124 EGEYNPRS------LTLCH-------NAYSD-------LEHFLQQGSFVVGNELSVADVSIHTTL 168

Human   169 LWLYKQVLEPSFRQAFPNTNRWFLTC---------INQPQFRAVLGEVKLCEKMAQFDAK 219
            :.|  .:|.|..|:.:|.|.:|....         ||....||:...:..|  ||:..||
  Fly   169 VTL--DLLIPVEREKYPQTKQWMERMDKLLPDNEEINLKGARALQTRILSC--MAENKAK 224

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
EEF1G	NP_001395.1	GST_N_EF1Bgamma	4..82	CDD:239342	21/86 (24%)
		GST_C_EF1Bgamma_like	91..213	CDD:198290	31/148 (21%)
		tolA	<212..>278	CDD:236545	4/8 (50%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	221..268
		EF1G	277..381	CDD:395522
GstE13	NP_001188889.1	GST_N_Delta_Epsilon	4..78	CDD:239343	19/80 (24%)
GstE13	NP_001188889.1	GST_C_Delta_Epsilon	92..211	CDD:198287	30/140 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810