DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment EEF1G and GstT4

DIOPT Version :9

Sequence 1:	NP_001395.1	Gene:	EEF1G / 1937	HGNCID:	3213	Length:	437	Species:	Homo sapiens
Sequence 2:	NP_572886.2	Gene:	GstT4 / 32299	FlyBaseID:	FBgn0030484	Length:	237	Species:	Drosophila melanogaster

Alignment Length:	270	Identity:	56/270 - (20%)
Similarity:	108/270 - (40%)	Gaps:	85/270 - (31%)

- Green bases have known domain annotations that are detailed below.

Human    32 LSAPPHFHFGQTNRTPEFLR-KFPAGKVPAFEG-----------------------------DDG 66
            :|.|..|:|...|::...|. ...|.|:| ||.                             |.|
  Fly     1 MSQPLKFYFDFLNQSSRALYILLEASKIP-FEAIPISMLKGEHLTGEFRDNVNRFRKLPAITDHG 64

Human    67 FCVFESNAIAYYVSNEELRGSTPE--------AAAQVVQWVSFADSDIVPPAST------WVFPT 117
            :.:.|:.||..:::.|:|   .||        ..:::.:::::..:: :..|:|      |:.|.
  Fly    65 YQLSENVAIFRHLAREKL---VPEHWYPRRHLGRSRIDEYLAWQQTN-MGVATTEYFQQKWLVPY 125

Human   118 LGIMHHNKQATENAKEEVRRILGLLD-AYLKTRTFLVGERVTLADITVVCTLLWLYKQVLEPSF- 180
            |........|...|.:::...|...: .:|.:|.|::|:.::.||::.:|       ::.:|..
  Fly   126 LQKTRPADNAVNLASKQLEHTLNEFEQLFLNSRKFMMGDNISYADLSAIC-------EIDQPKSI 183

Human   181 -RQAFPNTN---RWFLTCINQ--PQFRAVLGEVKLCEKMAQFDAKKFAETQPKKDTPRKEKGSRE 239
             ..||.|.|   ||:.|...:  |.::.||||         |:||            .|..||.:
  Fly   184 GYNAFQNRNKLARWYETVREELGPHYKEVLGE---------FEAK------------LKGSGSGQ 227

Human   240 EKQKPQAERK 249
            ::...||.::
  Fly   228 QQGVAQAVKQ 237

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
EEF1G	NP_001395.1	GST_N_EF1Bgamma	4..82	CDD:239342	16/79 (20%)
		GST_C_EF1Bgamma_like	91..213	CDD:198290	28/135 (21%)
		tolA	<212..>278	CDD:236545	8/38 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	221..268		5/29 (17%)
		EF1G	277..381	CDD:395522
GstT4	NP_572886.2	GST_N_Theta	5..80	CDD:239348	14/75 (19%)
GstT4	NP_572886.2	GST_C_Theta	95..220	CDD:198292	31/153 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900