DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment EEF1G and GstT2

DIOPT Version :9

Sequence 1:	NP_001395.1	Gene:	EEF1G / 1937	HGNCID:	3213	Length:	437	Species:	Homo sapiens
Sequence 2:	NP_724816.3	Gene:	GstT2 / 246386	FlyBaseID:	FBgn0050005	Length:	228	Species:	Drosophila melanogaster

Alignment Length:	212	Identity:	55/212 - (25%)
Similarity:	85/212 - (40%)	Gaps:	43/212 - (20%)

- Green bases have known domain annotations that are detailed below.

Human    47 PEFLRKFPA-----------GKVPAFEGDDGFCVFESNAIAYYVS-----NEELRGSTPEAAAQV 95
            |..||||..           .||||..|.| |.:.|:.||..|::     :|:|...|.|..|:|
  Fly    34 PIALRKFEQLTDEYKKINRFQKVPAIVGGD-FHLSETIAIIRYLADKGQFDEKLYPKTLENRARV 97

Human    96 VQWVSFADSDIVPPAS-----TWVFPTLGIMHHNK-QATENAKEEVRRILGLLDAYLKTRTFLVG 154
            .:::.:...:|....|     .|:||..||....| :..:...|.|...||||:.......||||
  Fly    98 DEFLEWQHLNIRLACSMYFRDAWLFPMNGIAPKPKPEQIQALIEGVENNLGLLERLWLENDFLVG 162

Human   155 ERVTLADITVVCTLLWLYKQVLEPSFR---QAFPNTNRWFLTCINQPQFRAVLGEVKLCEKMAQF 216
            :.:|:|||.....:    .|:....:|   :.||...:|             |..|::.......
  Fly   163 KNLTMADILGSSEI----NQLRLCQYRVDEKKFPKVVKW-------------LERVRVSANPYHD 210

Human   217 DAKKFAETQPKKDTPRK 233
            :...|.:.:.|:.|..|
  Fly   211 EGLTFIDRKSKQSTAAK 227

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
EEF1G	NP_001395.1	GST_N_EF1Bgamma	4..82	CDD:239342	16/50 (32%)
		GST_C_EF1Bgamma_like	91..213	CDD:198290	31/130 (24%)
		tolA	<212..>278	CDD:236545	4/22 (18%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	221..268		4/13 (31%)
		EF1G	277..381	CDD:395522
GstT2	NP_724816.3	GST_N_Theta	5..80	CDD:239348	16/46 (35%)
		GstA	7..202	CDD:223698	50/185 (27%)
		GST_C_family	93..218	CDD:295467	32/141 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810