Protein Alignment Abcd4 and Pmp70

DIOPT Version :9

• Sequence 1: NP_033018.2
• Gene: Abcd4 / 19300
• MGIID: 1349217
• Length: 606
• Species: Mus musculus
• Sequence 2: NP_001259732.1
• Gene: Pmp70 / 32992
• FlyBaseID: FBgn0031069
• Length: 665
• Species: Drosophila melanogaster
• Alignment Length: 624
• Identity: 167/624 - (26%)
• Similarity: 295/624 - (47%)
• Gaps: 77/624 - (12%)

Mouse    27 IQKVFFPS------------WSSQNVLMFMTLLCV--------------TLLEQLVIYQVGLIPS 65
            :..|||..            ||.:..|:|:....:              |::|..:|:.
  Fly    63 VNSVFFKQLRQLLPILIPGFWSVETGLLFLVAAALIGRSVSDIWMIQNATVVESTIIHM------ 121

Mouse    66 QYYGVLGNKDLDGFKALTLLAVTLIVLNSTLKSFDQFTCNLLYVSWRKDLTEHLHHLYFRARVYY 130
                     :...||...|..:|.:...|.:.:..:::...|.:.:|.:||.||:..|.....||
  Fly   122 ---------NRTKFKTALLKYLTALPAISVVTNVLKWSLGELKLRFRTNLTHHLYSQYLNGYTYY 177

Mouse   131 TLNVLRDDIDNPDQRISQDVERFCRQLSSVTSKLIISPFTLTYYTYQCFQSTGWLGPVSIFGYFI 195
            .::.|.:.|.|.||.::.|:::||...:.:.|.:......:..|.|:...:.|...|..:..|.:
  Fly   178 KMSNLDNRIANADQLLTTDIDKFCESATDLYSNISKPVLDIFIYVYRLTVNLGGKTPSILMLYLL 242

Mouse   196 VGTMVNKTLMGPIVTKLVQQEKLEGDFRFKHMQIRVNAEPAAFYRAGLVEHMRTDRRLQRLLQTQ 260
            ...:....|..|.....|:::||||:||:.:.::..|:|..|||:..:.|.:.......:|....
  Fly   243 FAGVFLTRLRRPTGRLTVEEQKLEGEFRYVNSRLITNSEEVAFYQGNVREKLTLLASYSKLRSHL 307

Mouse   261 RELMSRELWLYIGINTF-DYLGSILSYVVIAIPIFSG----VYGDLSPTELSTLVSKNAFVCIYL 320
            |:.:...:.:.|..|.. .|..||:.:..::||.||.    :.|:.|...|....:....: :.|
  Fly   308 RKFLEFRVSMGIIDNIIGKYFASIVGFYAVSIPFFSENHPLLSGENSGQRLQAYYTYGRML-VKL 371

Mouse   321 ISCFTQLIDLSTTLSDVAGYTHRIGELQEALLDMSRKSQD----------CEALGESEWDLDKTP 375
            .....:|:.....:|.:||:|.|:.||.:.|.|:::.:.:          ..|:|.:..:.....
  Fly   372 AEAIGRLVLAGREMSRLAGFTARMTELIKVLSDLNKGTYERTMVNGNNLAQNAVGSASSNFGPNK 436

Mouse   376 GCPTTEPSDTAFLLDRVSILAPSSDKPLIKDLSLKICEGQSLLITGNTGTGKTSLLRVLGGLWEG 440
            |....|  |.....::|.::.|:.| .|:::||.::..|.::|:.|..|.||:||.|:||.||..
  Fly   437 GIMCFE--DNIIRFEKVPLVTPNGD-VLLQELSFEVKSGTNVLVCGPNGCGKSSLFRILGELWPT 498

Mouse   441 MKGSVQMLADFGPHGVLF-LPQKPFFTDGTLREQVIYP-----LKEIYPDSGSADDERIVRFLEL 499
            ..|.|...:    .|.|| :||:|:.|.||||:|:|||     ::.:     ...||.::.:|::
  Fly   499 WGGKVTKPS----RGKLFYVPQRPYMTLGTLRDQIIYPHTRDDMRRL-----GHSDEDLMHYLDI 554

Mouse   500 AGLSSLVARTGGLDQQVDWNWYDVLSPGEMQRLSFARLFYLQPKYAVLDEATSALTEEAESELYR 564
            ..|:.|..|..|||...|  |.||||.||.||::.|||||.:|::|:|||.|||::.:.|.::|.
  Fly   555 VQLTYLEQRENGLDSIED--WIDVLSGGEKQRIAMARLFYHKPQFAILDECTSAVSVDVEGKMYS 617

Mouse   565 IGQQLGMTFISVGHRPSLEKFHSWVLRLHGGGSWELTRI 603
            ..:::|:|..:|.||.||...|.:.|:..|.||:|...|
  Fly   618 YCREVGITLFTVSHRKSLWAHHDYYLQFDGRGSYEFATI 656

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Abcd4	NP_033018.2	YddA	10..606	CDD:226646	167/624 (27%)
		ABC_membrane_2	16..294	CDD:284003	62/293 (21%)
		ABCD_peroxisomal_ALDP	387..598	CDD:213190	81/216 (38%)
Pmp70	NP_001259732.1	3a01203	3..653	CDD:273360	165/619 (27%)
		ABC_membrane_2	63..342	CDD:284003	62/293 (21%)
		ABCD_peroxisomal_ALDP	446..651	CDD:213190	81/216 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4178
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D146647at33208
OrthoFinder	1	1.000	-	-		FOG0000393
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100236
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X313
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.720