DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptprm and Ptp61F

DIOPT Version :9

Sequence 1:	NP_001344554.1	Gene:	Ptprm / 19274	MGIID:	102694	Length:	1486	Species:	Mus musculus
Sequence 2:	NP_476687.1	Gene:	Ptp61F / 38160	FlyBaseID:	FBgn0267487	Length:	548	Species:	Drosophila melanogaster

Alignment Length:	307	Identity:	100/307 - (32%)
Similarity:	160/307 - (52%)	Gaps:	28/307 - (9%)

- Green bases have known domain annotations that are detailed below.

Mouse   952 AKKDENRMKNRYGNIIAYDHSRVRLQMLEGDNNSDYINGNYIDGYHRPNHYIATQGPMQETIYDF 1016
            :::..||..|||.::..|||||:.|:.    .:.||||.|.:........||.||||:.:|:..|
  Fly    55 SERHTNRGLNRYRDVNPYDHSRIVLKR----GSVDYINANLVQLERAERQYILTQGPLVDTVGHF 115

Mouse  1017 WRMVWHENTASIIMVTNLVEVGRVKCCKYWPDDTEIYKDIK-------VTLIDTELLAEYVIRTF 1074
            |.|||.:.:.:::|:..|:|..::||..|||::....|.:|       |.|:..|....:|.|.|
  Fly   116 WLMVWEQKSRAVLMLNKLMEKKQIKCHLYWPNEMGADKALKLPHVKLTVELVRLETYQNFVRRWF 180

Mouse  1075 AVEKRGIHEIREIRQFHFTGWPDHGVPYHATGLLGFVRQVKSKS--PPNAGPLVVHCSAGAGRTG 1137
            .:......:.||:.|||:|.|||.|:|......|.|::||:...  ..:.||.|||||||.||:|
  Fly   181 KLTDLETQQSREVMQFHYTTWPDFGIPSSPNAFLKFLQQVRDSGCLSRDVGPAVVHCSAGIGRSG 245

Mouse  1138 CFIVIDIMLDMAEREGVVDIYNCVRELRSRRVNMVQTEEQYVFIHDAILEACLCGDTSIPASQVR 1202
            .|.::|..|.:.::.|..::...:.||||.|:.::||.:|..|.:.||:|.            ::
  Fly   246 TFCLVDCCLVLIDKYGECNVSKVLCELRSYRMGLIQTADQLDFSYQAIIEG------------IK 298

Mouse  1203 SLYYDMNKLDPQTNSSQIKEEFRTLNMVTPTL--RVEDCSIALLPRN 1247
            .| :|...||.:........|..||:.:.|.|  ||:..::.|.|.:
  Fly   299 KL-HDPTFLDAEEPLISNDTETHTLDELPPPLPPRVQSLNLPLAPNS 344

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptprm	NP_001344554.1	MAM	22..182	CDD:214533
		ig	192..274	CDD:278476
		FN3	282..361	CDD:214495
		FN3	383..467	CDD:214495
		fn3	499..574	CDD:306538
		PTPc	933..1187	CDD:214550	86/243 (35%)
		PTPc	1249..1481	CDD:238006
Ptp61F	NP_476687.1	PTPc	34..295	CDD:214550	86/243 (35%)
Ptp61F	NP_476687.1	PTPc	62..295	CDD:238006	84/236 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910