Protein Alignment Ptprm and Ptp36E

DIOPT Version :9

• Sequence 1: NP_001344554.1
• Gene: Ptprm / 19274
• MGIID: 102694
• Length: 1486
• Species: Mus musculus
• Sequence 2: NP_001286033.1
• Gene: Ptp36E / 35091
• FlyBaseID: FBgn0267486
• Length: 682
• Species: Drosophila melanogaster
• Alignment Length: 643
• Identity: 202/643 - (31%)
• Similarity: 336/643 - (52%)
• Gaps: 64/643 - (9%)

Mouse   892 PHTYK--------------KREAAD--------VPYQTGQLHPAIRVADLLQHITQMKCAEGYGF 934
            |:|.|              |.||.|        :|.....:...:::.||.:....:       :
  Fly    45 PNTIKLSMLNSGLLSFERIKLEARDENNSLSKTIPNGPIDIRHFLKLCDLRRKFPVL-------Y 102

Mouse   935 KEEYESFFEGQSAPWDSAKKDENRMKNRYGNIIAYDHSRVRLQMLEGDNNSDYINGNYIDGYHRP 999
            |.|:::..:.:|.....|.|..|..||:....|.||::||.|:.:.|..:|||:|.:|:|...:|
  Fly   103 KLEFQTAAKVESNTCRHALKKNNLEKNQNPKCIPYDYNRVVLEKVGGLQDSDYVNASYVDSLLKP 167

Mouse  1000 NHYIATQGPMQETIYDFWRMVWHENTASIIMVTNLVEVGRVKCCKYWPDDTEI---YKDIKVTLI 1061
            |.||.||||::||:..:|||||.||.::|:|:|...:..:|.|.:|||.:.|:   |.||.:.::
  Fly   168 NAYIVTQGPVEETVQAYWRMVWQENISAIVMLTKTFDFAKVMCHQYWPPNMEVHEQYGDIFINIV 232

Mouse  1062 DTELLAEYVIRTFAV----EKRGIHEIREIRQFHFTGWPDHGVPYHATGLLGFVRQVK------- 1115
            ..|.||.:.||||.:    ||:.:.:.|.|.|||:|.|..|..|: :..||.|.|:|:
  Fly   233 REEQLANFHIRTFRLYKMNEKQEVTDERLILQFHYTEWYSHSCPF-SNALLEFRRRVRLVVGNII 296

Mouse  1116 SKSPPNAGPLVVHCSAGAGRTGCFIVIDIMLDMAEREGVVDIYNCVRELRSRRVNMVQTEEQYVF 1180
            .......||::||||.|.||:|.::.||..|::||.|...:::..:::||..|..:|:..|||.|
  Fly   297 KDEDDMRGPILVHCSDGGGRSGVYMSIDANLELAEEEECFNVFGYLKKLRQSRKGLVENVEQYKF 361

Mouse  1181 IHDAILEACLCGDTSIPASQVRSLYYDMNKLDPQTNSSQIKEEFRTLNMVTPTLRVEDCSIALLP 1245
            |:|.:.|..:||.|..|.|::........:.:..|..::.:.|:..:...||...:.||:.....
  Fly   362 IYDTLEEHIICGKTWFPVSELSDRLKAKARRNSGTKMNEYQAEYDQICKQTPRFTIGDCAGGHRA 426

Mouse  1246 RNHEKNRCMDILPPDRCLPFLITIDGES-SNYINAALMDSYKQPSAFIVTQHPLPNTVKDFWRLV 1309
            .|.||||.:..:|||...|:|.:..|.: ::|||:..:|.|.:|..:|||:.|:.:|:.:||.||
  Fly   427 DNREKNRDVLCVPPDNFRPYLTSFQGNAFTDYINSVFVDGYTKPREYIVTEWPMKHTLGEFWSLV 491

Mouse  1310 LDYHCTSVVML-NDVDPAQLCPQYWP-ENGVHRHGPI-QVEFVSA-----------DLEEDIISR 1360
            .|..|::||:| .....:|..|.:|| ::.:.::||: .|.:|.:           .:.:.|:|.
  Fly   492 YDQECSAVVVLCQPPSQSQQYPSFWPNKSKMEKYGPVFSVHYVMSKSYTNIKQWEFKINKKIVSL 556

Mouse  1361 IFRIYNASRPQDGHRMVQQFQFLGWPMYRDTPVSKRSFLKLIRQVDKWQEEYNGGEGRTVVHCLN 1425
            ...:.....|.   |.||.||...|||....|.|..|.:.|:..|:.|:.:.:  .|...|...:
  Fly   557 TEMMAGVKAPT---RTVQLFQLTCWPMGHKVPSSTNSLVYLMNMVEIWRNKVD--YGPVCVVSPD 616

Mouse  1426 GGGRSGTFCAISIVCEMLRHQRTVDVFHAVKTLRNNKPNMVDLLDQYKFCYEVALEYL 1483
            |..|:|.:||.:...|.:.....||||.||||:|.::|.:|:.:.:||:||::.|.|:
  Fly   617 GRSRAGVYCAANACIEQVIQHGEVDVFQAVKTVRRHRPQLVENMTEYKYCYDLVLHYV 674

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptprm	NP_001344554.1	MAM	22..182	CDD:214533
		ig	192..274	CDD:278476
		FN3	282..361	CDD:214495
		FN3	383..467	CDD:214495
		fn3	499..574	CDD:306538
		PTPc	933..1187	CDD:214550	99/267 (37%)
		PTPc	1249..1481	CDD:238006	78/246 (32%)
Ptp36E	NP_001286033.1	Y_phosphatase	125..368	CDD:395053	94/243 (39%)
		Y_phosphatase	428..671	CDD:395053	79/247 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG4228
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000829
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.770