Protein Alignment Ptprm and Wsck

DIOPT Version :9

• Sequence 1: NP_001344554.1
• Gene: Ptprm / 19274
• MGIID: 102694
• Length: 1486
• Species: Mus musculus
• Sequence 2: NP_733018.1
• Gene: Wsck / 318600
• FlyBaseID: FBgn0046685
• Length: 791
• Species: Drosophila melanogaster
• Alignment Length: 573
• Identity: 113/573 - (19%)
• Similarity: 176/573 - (30%)
• Gaps: 214/573 - (37%)

Mouse   519 TYKAVSSFDPEIDLSNQSGRVSKLGNETHFLFFGLYPGTTYSFTIR-----ASTAKGFGPPATNQ 578
            ||.::.:| |:.:...||       .||.|....|:|.|.|:.::|     |...:.....|:.:
  Fly   184 TYSSLPAF-PQPEFMVQS-------TETQFELTDLHPATLYNISVRAMCKDAQVGQSECGQASIE 240

Mouse   579 FTTKISAPS-MPAYEFETP--LNQTDNTVTVMLKPAQSRGAPVSVYQIVVEEERPRRTKKTTEIL 640
            .||::..|| :||    .|  |::||.|||:.|.|.::...|:|...::||           .:.
  Fly   241 ATTEVGLPSPVPA----QPKILSRTDRTVTIELSPIRNDNGPLSKLLVIVE-----------YVD 290

Mouse   641 KCYPVPIHFQNASILNS---------QYYFAAEF----PADSLQAAQPFTIGDNKTYNGYWNTPL 692
            .....|.   :|.:|.|         .||.|||.    |.|:  ..:.|.:||.|.|..:.|.||
  Fly   291 NALSQPF---DAQLLGSWQQAQQDGVPYYIAAELDYDRPEDN--RTRRFVVGDGKRYGRFTNKPL 350

Mouse   693 -LPHKSYRIYYQAASRANGETK----------------------------------IDCV----- 717
             .|.....|.....|...|.||                                  :.||
  Fly   351 DQPDAHVHISLGLVSTLEGVTKTMYSRGTHDQHVTSLDDFSYATFEKGQSSVVALAVTCVIFGSC 415

Mouse   718 ---------------------------RVATKAAII------------------------VTQLT 731
                                       .:..:..||                        :.||.
  Fly   416 LLLSLIAYFYLRYKTCRGRRLTGGNTHEMTLQTPIIERENNGYLVEDDPLPHSPENFKQQLQQLV 480

Mouse   732 TPYIRIAPAA---------GDGQ----LTGAVTPKPVP--------------------------- 756
            ..|.||...|         |||:    :||.|:.....
  Fly   481 EGYERIPRNALRLNVNDVIGDGRFGEIITGKVSTNDFARDCTLHVLCLDDLNGTTQAQLLRELRQ 545

Mouse   757 -EPEKQTDHTVKIAGVIAGILLFVIIFLGVVLVMKKRKLAKKRKETMSSTRQEMTVMVNSMDKSY 820
             ...|:.:|.:...||.|....|.:||       ::::::.|||...|........:.:..::..
  Fly   546 LSQLKRQEHLLDFYGVSASPDWFYLIF-------EQQRMSLKRKLVESRLMAPSPRLTSLSEQLV 603

Mouse   821 AEQGTNCDEAFSFMGTHNLNGRSVSSPSSFTMKTNTLSTSVPNSYYPDPFVPTAILDETHTMASD 885
            .:.......|.:::.:..:..|.:.|.|.|......|..||   :.|.|::..|.....|.....
  Fly   604 LQWIYELASAMNYLSSCQVVHRQLCSHSVFVTSDFKLKLSV---FGPLPYMNIARQQPDHNRWLA 665

Mouse   886 TSSLAQPHTYKKREAADV----------------PYQTG-----QLHPAIRVA 917
            ...|...|.:..|  :||                ||...     ||..|||.|
  Fly   666 PEVLRHQHHHSTR--SDVWSLACVAWECCALGGTPYANAVASNQQLLEAIRAA 716

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptprm	NP_001344554.1	MAM	22..182	CDD:214533
		ig	192..274	CDD:278476
		FN3	282..361	CDD:214495
		FN3	383..467	CDD:214495
		fn3	499..574	CDD:306538	15/59 (25%)
		PTPc	933..1187	CDD:214550
		PTPc	1249..1481	CDD:238006
Wsck	NP_733018.1	WSC	42..115	CDD:280068
		fn3	130..222	CDD:278470	13/45 (29%)
		TyrKc	493..746	CDD:197581	43/236 (18%)
		PTKc	497..750	CDD:270623	43/232 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	58	1.000	Domainoid score	I10721
eggNOG	1	0.900	-	-		E2759_KOG4228
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.900