Protein Alignment Ptpru and Ptp36E

DIOPT Version :9

• Sequence 1: XP_011248512.1
• Gene: Ptpru / 19273
• MGIID: 1321151
• Length: 1473
• Species: Mus musculus
• Sequence 2: NP_001286033.1
• Gene: Ptp36E / 35091
• FlyBaseID: FBgn0267486
• Length: 682
• Species: Drosophila melanogaster
• Alignment Length: 575
• Identity: 180/575 - (31%)
• Similarity: 296/575 - (51%)
• Gaps: 47/575 - (8%)

Mouse   918 KKDKLKGGRQEPVSAYDRHHVKLHPMLADPDADYISANYIDIRINRQGYHRSNHFIATQGDLAQG 982
            ||:.|:..:......||.:.|.|..:....|:||::|:|:|..:      :.|.:|.||
  Fly   122 KKNNLEKNQNPKCIPYDYNRVVLEKVGGLQDSDYVNASYVDSLL------KPNAYIVTQ------ 174

Mouse   983 QAPSAPPGPKPEMIYDFWRMVWQEQCASIVMITKLVEVGRVKCSRYWP---EDSDMYGDIKITLV 1044
                   ||..|.:..:|||||||..::|||:||..:..:|.|.:|||   |..:.||||.|.:|
  Fly   175 -------GPVEETVQAYWRMVWQENISAIVMLTKTFDFAKVMCHQYWPPNMEVHEQYGDIFINIV 232

Mouse  1045 KTETLAEYVVRTFAL----ERRGYSARHEVRQFHFTAWPEHGVPYHATGLLAFIRRVK------- 1098
            :.|.||.:.:|||.|    |::..:....:.|||:|.|..|..|: :..||.|.|||:
  Fly   233 REEQLANFHIRTFRLYKMNEKQEVTDERLILQFHYTEWYSHSCPF-SNALLEFRRRVRLVVGNII 296

Mouse  1099 ASTPPDAGPIVIHCSAGTGRTGCYIVLDVMLDMAECEGVVDIYNCVKTLCSRRVNMIQTEEQYIF 1163
            .......|||::|||.|.||:|.|:.:|..|::||.|...:::..:|.|...|..:::..|||.|
  Fly   297 KDEDDMRGPILVHCSDGGGRSGVYMSIDANLELAEEEECFNVFGYLKKLRQSRKGLVENVEQYKF 361

Mouse  1164 IHDAILEACLCGETTIPVNEFKATYREMIRIDPQSNSSQLREEFQTLNSVTPPLDVEECSIALLP 1228
            |:|.:.|..:||:|..||:|.....:...|.:..:..::.:.|:..:...||...:.:|:.....
  Fly   362 IYDTLEEHIICGKTWFPVSELSDRLKAKARRNSGTKMNEYQAEYDQICKQTPRFTIGDCAGGHRA 426

Mouse  1229 RNRDKNRSMDVLPPDRCLPFLISSDGDP-NNYINAALTDSYTRSAAFIVTLHPLQSTTPDFWRLV 1292
            .||:|||.:..:|||...|:|.|..|:. .:|||:...|.||:...:|||..|::.|..:||.||
  Fly   427 DNREKNRDVLCVPPDNFRPYLTSFQGNAFTDYINSVFVDGYTKPREYIVTEWPMKHTLGEFWSLV 491

Mouse  1293 YDYGCTSIVMLNQLNQSNSAWPCLQYWPEPGR-QQYG-LMEVEFVSGTANEDLVSRVFRVQNS-- 1353
            ||..|:::|:|.|....:..:|  .:||...: ::|| :..|.:|...:..::....|::...
  Fly   492 YDQECSAVVVLCQPPSQSQQYP--SFWPNKSKMEKYGPVFSVHYVMSKSYTNIKQWEFKINKKIV 554

Mouse  1354 --SRLQEG----HLLVRHFQFLRWSAYRDTPDSRKAFLHLLAEVDKWQAESGDGRTVVHCLNGGG 1412
              :.:..|    ...|:.||...|......|.|..:.::|:..|:.|:.:...|...|...:|..
  Fly   555 SLTEMMAGVKAPTRTVQLFQLTCWPMGHKVPSSTNSLVYLMNMVEIWRNKVDYGPVCVVSPDGRS 619

Mouse  1413 RSGTFCACATVLEMIRCHSLVDVFFAAKTLRNYKPNMVETMDQYHFCYDVALEYL 1467
            |:|.:||....:|.:..|..||||.|.||:|.::|.:||.|.:|.:|||:.|.|:
  Fly   620 RAGVYCAANACIEQVIQHGEVDVFQAVKTVRRHRPQLVENMTEYKYCYDLVLHYV 674

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpru	XP_011248512.1	MAM	31..194	CDD:214533
		IG	204..290	CDD:214652
		fn3	299..373	CDD:365830
		FN3	394..489	CDD:238020
		fn3	502..585	CDD:365830
		PTP_DSP_cys	951..1174	CDD:391942	82/236 (35%)
		R-PTPc-U-2	1259..1465	CDD:350485	64/215 (30%)
Ptp36E	NP_001286033.1	Y_phosphatase	125..368	CDD:395053	88/262 (34%)
		Y_phosphatase	428..671	CDD:395053	76/244 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG4228
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000829
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	5	4.770