Protein Alignment Ptpn18 and CG42327

DIOPT Version :10

• Sequence 1: NP_035336.2
• Gene: Ptpn18 / 19253
• MGIID: 108410
• Length: 453
• Species: Mus musculus
• Sequence 2: NP_001036706.2
• Gene: CG42327 / 41401
• FlyBaseID: FBgn0259227
• Length: 1429
• Species: Drosophila melanogaster
• Alignment Length: 353
• Identity: 105/353 - (29%)
• Similarity: 155/353 - (43%)
• Gaps: 73/353 - (20%)

Mouse     3 RHTDLVRSFLEQLEARDYREGAILAREFSDIKARSVAWKSEGVCSTKAGSRLGNTNKNRYKDVVA 67
            ||..|..|.|    ||.....:.:..||.|:.  .:..:::.|..       |..:||||.:|:.
  Fly  1092 RHNLLTASEL----ARFVERRSDVFEEFRDVP--QIIARADEVPP-------GCEDKNRYANVIP 1143

Mouse    68 YDETRVILSLLQEEGHGDYINANFIRG-IDGSQAYIATQGPLPHTLLDFWRLVWEFGVKVILMAC 131
            ..||||:|....::...:|||||::|| .|....|||.|.||..|..||||::||...:||:.|.
  Fly  1144 LPETRVVLQRQGDDDKTEYINANYVRGPRDAPNYYIACQAPLESTTSDFWRMIWEQQSRVIIQAT 1208

Mouse   132 QETENGRRKCERYW---AREQEPLKAGPFCITLT-KETTLNADITLRTLQVTFQKEFRSVHQLQY 192
            ..:|||..:|..|.   |........|.:.:||. :|......|:...|:....:|.|.:....|
  Fly  1209 DLSENGIERCAEYLPPSATLDNHSSYGDYQVTLKHREVKDRYAISTLVLKRVDGEESRELTHYWY 1273

Mouse   193 MSWPDHGVPSSSDHILTMVEEARC----------------------------------------L 217
             .||:.|||:....|:.|:.|||.                                        :
  Fly  1274 -KWPEAGVPAEEAPIIAMLLEARSSLKSYSLEQANELREKSATLETSMDADGSKAEAGSTSSHEI 1337

Mouse   218 QG---------LGPGPLCVHCSAGCGRTGVLCAVDY-VRQLLLTQTIPPNFSLFQVVLEMRKQRP 272
            .|         ...|||.||||.|.||||.:.|.|. :|.|   :|...:..:.|:|..:|:.|.
  Fly  1338 NGNISSRSGTRSQQGPLTVHCSPGTGRTGTIIASDMAIRSL---ETPKRSVDIPQLVYYVRRGRA 1399

Mouse   273 AAVQTEEQYRFLYHTVAQLFSRTLQDTS 300
            :||||:|||.|:| .||.:::..:.:.|
  Fly  1400 SAVQTKEQYEFIY-KVASMYAAKITNLS 1426

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpn18	NP_035336.2	PTP_DSP_cys	27..292	CDD:475123	97/319 (30%)
		PRK12323	<331..>452	CDD:481241
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	384..453
CG42327	NP_001036706.2	PTPc	1134..1415	CDD:214550	90/285 (32%)