DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dusp1 and CG10089

DIOPT Version :9

Sequence 1:	NP_038670.1	Gene:	Dusp1 / 19252	MGIID:	105120	Length:	367	Species:	Mus musculus
Sequence 2:	NP_001261803.1	Gene:	CG10089 / 39517	FlyBaseID:	FBgn0036369	Length:	447	Species:	Drosophila melanogaster

Alignment Length:	169	Identity:	47/169 - (27%)
Similarity:	80/169 - (47%)	Gaps:	4/169 - (2%)

- Green bases have known domain annotations that are detailed below.

Mouse   176 EILSFLYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNHKADISSWFNEA 240
            ::|..||:|:...:.....|:...|:.:|.:. :.|........|..:...|....::|.:|:..
  Fly     7 KVLPGLYVGNYRDSKDHAQLERFKISHIIAIH-DSPRRLLPDKHYLCVMASDTPDQNLSQYFSVC 70

Mouse   241 IDFIDSIKDAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNFSFMGQL 305
            .|||.:.:...|.|.:||.||:|||.|:.:||:|....:...||.:.|:..|::.:||..|..||
  Fly    71 NDFIHAARLREGNVLIHCLAGMSRSVTVAVAYIMTATHLNWKEALKVVRAGRAVANPNAGFQSQL 135

Mouse   306 LQFESQVLAP---HCSAEAGSPAMAVLDRGTSTTTVFNF 341
            .:||...|:.   .......|.|:..|||....|.:.|:
  Fly   136 QEFEQFKLSEERRRLRERFPSSALEQLDRTKVATALDNY 174

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dusp1	NP_038670.1	DSP_MapKP	7..136	CDD:238723
		DSPc	173..309	CDD:238073	37/132 (28%)
		CDC14	188..313	CDD:225297	35/124 (28%)
CG10089	NP_001261803.1	DSPc	4..139	CDD:238073	37/132 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1716
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1576308at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820