Protein Alignment CG12084 and F44E5.2

DIOPT Version :10

• Sequence 1: NP_612112.1
• Gene: CG12084 / 192509
• FlyBaseID: FBgn0043458
• Length: 793
• Species: Drosophila melanogaster
• Sequence 2: NP_496512.2
• Gene: F44E5.2 / 185735
• WormBaseID: WBGene00009689
• Length: 489
• Species: Caenorhabditis elegans
• Alignment Length: 481
• Identity: 97/481 - (20%)
• Similarity: 179/481 - (37%)
• Gaps: 156/481 - (32%)

  Fly   109 KLFALSLW----YCDMIS------------VGSHHLLAHYGDSLRSLELGISSHLLQYAEPNEKE 157
            ||.||.:.    ||..||            |.:.|:.....:.:.||.:|....:.|..:.:::.
 Worm    38 KLVALDIELDPNYCLQISRKLNITKAVCKNVTTEHIKLLSNNCILSLTIGNIDKVKQVYQDDKEN 102

  Fly   158 PVDFQLTCPHLRRLVLNGVVMHHRLQFAHLHDLGHLDLTSCVLANFSL-EALG-SLPNLHTLILF 220
            |:      .::.|| |..|:.....|     :|.:||:....|.:::. :||| .||:|.|||:.
 Worm   103 PI------INIARL-LEDVLGEESRQ-----NLQYLDIQGNELFSYNWPKALGHMLPSLQTLIVC 155

  Fly   221 NVWPIANQLHAIC-CLRRLCTLDISISSSGNGHG------------------TYDLPDQTLEM-- 264
            ....|.::...:| ....|..||||.::.||..|                  :||...:..|:
 Worm   156 QRSFINDEFSQLCNSFPNLHKLDISDTNIGNLSGISNLKNLQKLCMMNLEFESYDDIKELFEVKS 220

  Fly   265 -----------------------LMDNLRHLTHLDISGTNLAGNGVATKESTTTSGMQQS-PKME 305
                                   |.:.|..|..||.||||:      .|||.:|  :|.| |.::
 Worm   221 LRVLNISRDRKDFKPSLIMQYIQLKEVLPELRFLDCSGTNV------DKESIST--IQNSHPNLK 277

  Fly   306 QHFALTDIPGLASRTQRPLQFLGLYHTAHWACKRHDIPALEVAGDANEQQILTAARYY----HDR 366
            :..||.: ||                      |...:|.:::....:....|....:|    ||
 Worm   278 KVAALCE-PG----------------------KNFIVPEIKILNSIDLGSTLKCLEHYTTLKHD- 318

  Fly   367 PVLLTRVLNDLYHL----FRFEN--CKDIHTALDVVLSAMDRHLKFKHMQISGSATLFYIVKGRD 425
             |.:::.|:.|::.    :..:|  .:.::.|::...|        .::||.|.|.|..|||...
 Worm   319 -VFMSQCLHALFNFIKSSYHIDNEWIQYVYRAINTCSS--------DNVQIQGGACLSLIVKKSI 374

  Fly   426 RSK-------FGALLRNHIIRTLLNGMEMHITDDTMLRNGYLTLTQFHMPVDVLFEYERLIKILL 483
            ::.       ...:.:..:.:|..|..:.:..|.|:|....::|              .::|.:.
 Worm   375 KTMRPYEVALSRVVCKGSVAKTFYNASKPNSWDLTVLERKVVSL--------------EVLKPIA 425

  Fly   484 HGVSKTEQEGFVQRIAIYLLNTLACQ 509
            :|:...:         :.::|.|.|:
 Worm   426 YGIIVRD---------MCMINILNCK 442

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12084	NP_612112.1	leucine-rich repeat	110..135	CDD:275381	9/40 (23%)
		leucine-rich repeat	136..167	CDD:275381	5/30 (17%)
		leucine-rich repeat	168..189	CDD:275381	5/20 (25%)
		LRR	<184..>282	CDD:443914	34/143 (24%)
		leucine-rich repeat	190..213	CDD:275381	8/24 (33%)
F44E5.2	NP_496512.2	LRR	22..>278	CDD:443914	62/259 (24%)
		leucine-rich repeat	123..148	CDD:275380	8/24 (33%)
		leucine-rich repeat	149..173	CDD:275380	6/23 (26%)
		leucine-rich repeat	174..195	CDD:275380	8/20 (40%)