Protein Alignment CG12084 and gadr-4

DIOPT Version :9

• Sequence 1: NP_612112.1
• Gene: CG12084 / 192509
• FlyBaseID: FBgn0043458
• Length: 793
• Species: Drosophila melanogaster
• Sequence 2: NP_001317764.1
• Gene: gadr-4 / 173745
• WormBaseID: WBGene00021053
• Length: 797
• Species: Caenorhabditis elegans
• Alignment Length: 709
• Identity: 135/709 - (19%)
• Similarity: 227/709 - (32%)
• Gaps: 235/709 - (33%)

  Fly    15 EEPLTLKEIAYQKLCNNLDIISSHRPDGQRGLNPGIVLPNEIC---DGFLENYQRFNRPLDDSVI 76
            |.|||       :.||....           |.|.:|:....|   .|..:|.|....|.....|
 Worm    79 EFPLT-------RFCNFYGT-----------LTPLMVIKKTACYIYRGLFDNVQYELDPKSSEKI 125

  Fly    77 R--LFED--THRTSLKIVNLRNSTLSSIGLETLMRHKLFALSLWYCDMISVGSHHLLAH---YGD 134
            .  |..|  |:|...:|:...|......|.:.|.|..|..|.......|.:|...|:.:   ...
 Worm   126 YEILMNDGWTYRIKEQIIEKFNLITMDFGKKRLYRGILDILKAMPIQSIKLGKLDLIENDYKQRS 190

  Fly   135 SLRSLELGI---------SSHLLQYAEPNEKEPV----------------------------DFQ 162
            ...|:::.:         |..|||:.:...:|.:                            :|.
 Worm   191 DKSSIDISMLIKSALSDNSRALLQHLDIEGREVLSINWPRKIGLLLPSLASLHVKGRSFFVFEFT 255

  Fly   163 LTCPHLRRLV-----------LNGV-----------------VMHHRLQFAHLHDLGHLDLT--- 196
            ..|.....|:           |||:                 ...|.:...:|.:|..||::
 Worm   256 QLCRSFPNLISLNISGTNIKNLNGISALKRLEVLSMQFLEIETTEHLINLFNLSNLKFLDISDIP 320

  Fly   197 ---SCVLANFSLEALGSLPNLHTLILFNVWPIANQLHAICCLRRLCTLDISISSSGNGHGTYDLP 258
               ||::.:..:|....||||..:.                    ||             ..|:.
 Worm   321 EYDSCIIVHLYVECGKGLPNLKFMD--------------------CT-------------ATDIN 352

  Fly   259 DQTLEMLMDNLRHLTHLDISGTNL---AGNGVATK-----ESTTTSGMQQSPKMEQHF----ALT 311
            :..||.::.:...|..:....|||   :.:||...     :|..||.:|.| ::..|:    ...
 Worm   353 NDLLEKILISHPKLETISAIVTNLHRVSDSGVCVLQTDAIDSAVTSLIQCS-RLNLHYLAEKCFY 416

  Fly   312 DIPGL--------ASRTQRPLQFLGLYHTAHWAC---KRHDIPAL-EVAGDANEQQILTAARYYH 364
            :|..|        ||...|  :.:.|..|:  :|   |:|.|..| |:|  .::.|.||..
 Worm   417 EIRDLLESGQHFNASEFLR--KIINLIETS--SCPIRKKHGISYLIELA--EHQCQKLTLL---- 471

  Fly   365 DRPVLLTRVLNDLYHL-----FRFENCK---DIHTALDVVLSAMDRHLKFKHMQISGSATLFYIV 421
            :..:||..:||.:..|     :..||..   .:..|||.:.::.:.|  |.:.:|...|..:.:.
 Worm   472 EVSILLDTLLNQVLELPEIDDYLSENKSYNISMWCALDNLTNSENHH--FNYDKICWVAVKYLVT 534

  Fly   422 KGRDRSKFGALLRNHIIRTLLNGMEMHITDDTMLR-NGYLTLTQFHMPVDVLFEYERLIKILLHG 485
            |...|.....    .::....|.....|...::.| |.::               :|::.||..|
 Worm   535 KPNSRETRAV----EVLEKYFNSSMSRIWLISIARQNNFM---------------KRIVNILGRG 580

  Fly   486 VSKTEQEGFVQRI---------------------AIYLLNTLACQVDGRQKLFLGELGVVSTMFT 529
            :.:.|:...|..|                     .|.|::...|:.:..|...|    .:|...|
 Worm   581 LGRNEKYVSVLNILTPLVECCDEACHNLVEHYGHRILLVDLKDCEDETAQLKIL----YISVQLT 641

  Fly   530 LIKDRLTRSVFDDVMEVAWSTM------WNVTDETAINCKRFLDGRGMEYFLKCLHTFP 582
            ..::.....:|.|  ::.:|.:      |.  |..|.....||   ....||...||||
 Worm   642 RFQNYEMLKIFHD--DLFFSDIKKMPNRWE--DNRAYQAFSFL---AQLQFLSESHTFP 693

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12084	NP_612112.1	leucine-rich repeat	110..135	CDD:275381	5/27 (19%)
		leucine-rich repeat	136..167	CDD:275381	8/67 (12%)
		leucine-rich repeat	168..189	CDD:275381	6/48 (13%)
		leucine-rich repeat	190..213	CDD:275381	7/28 (25%)
		ARM	535..628	CDD:237987	14/54 (26%)
gadr-4	NP_001317764.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3665
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810