Protein Alignment CG12084 and LOC1276632

DIOPT Version :10

• Sequence 1: NP_612112.1
• Gene: CG12084 / 192509
• FlyBaseID: FBgn0043458
• Length: 793
• Species: Drosophila melanogaster
• Sequence 2: XP_061501346.1
• Gene: LOC1276632 / 1276632
• VectorBaseID: AGAMI1_006473
• Length: 770
• Species: Anopheles gambiae
• Alignment Length: 787
• Identity: 475/787 - (60%)
• Similarity: 588/787 - (74%)
• Gaps: 42/787 - (5%)

  Fly     4 KVRLMEDGSLDEEPLTLKEIAYQKLCNNLDIISSHRP-DGQRGLNPGIVLPNEICDGFLENYQRF 67
            :|||.|:|.:|||..||.|::.:.:..||.:|.:..| ..|..|...:|:||||||.||...|..
Mosquito     4 RVRLKENGIMDEELPTLMELSIRFMAKNLHVICNTDPVTHQLELKDDVVVPNEICDRFLRYQQDC 68

  Fly    68 NRPLDDSVIRLFEDTHRTSLKIVNLRNSTLSSIGLETLMRHKLFALSLWYCDMISVGSHHLLAHY 132
            .:.::|..|::|.||.:|.|:.|:|||||:::.|:..|:||:|.:||:|||:.|:..|.::|..:
Mosquito    69 GQDINDRFIQIFRDTEKTPLRHVSLRNSTITNEGMRILLRHQLNSLSMWYCNKITTASWNILIEH 133

  Fly   133 GDSLRSLELGISSHLLQYAEPNEKEPVDFQLTCPHLRRLVLNGVVMHHRLQFAHLHDLGHLDLTS 197
            ...|||||||....:|:::|||||.|:||||..|.|:||.|||||:...:||:||.:|.|||||:
Mosquito   134 CRQLRSLELGRFVDMLKHSEPNEKTPIDFQLLLPRLQRLKLNGVVLQPTIQFSHLTELSHLDLTA 198

  Fly   198 CVLANFSLEALGSLPNLHTLILFNVWPIANQLHAICCLRRLCTLDISISSSGNGHGTYDLPDQTL 262
            |:.|.|||:||..||||.|||||||||:.::...:|.|:.|.|||:|:|.: |..|.|..|::.|
Mosquito   199 CIFAEFSLKALVDLPNLRTLILFNVWPLEHEFPTLCKLKNLETLDLSVSRA-NVDGNYLTPNKLL 262

  Fly   263 EMLMDNLRHLTHLDISGTNLAGNGVATKESTTTSGMQQSPKMEQHFALTDIPGLASRTQRPLQFL 327
            ..|::||..|.|||||||||||:|||.:..:.|.            :.:|||||.||..|||.||
Mosquito   263 ANLVENLPKLRHLDISGTNLAGDGVAERAGSCTG------------SSSDIPGLVSRVDRPLDFL 315

  Fly   328 GLYHTAHWACKRHDIPALEVAGDANEQQILTAARYYHDRPVLLTRVLNDLYHLFRFENCKDIHTA 392
            |:|:|:|.|||.||||||.:||:|.|:|||.||..|.||..|||:||||||||.|||.||.||.|
Mosquito   316 GIYYTSHSACKWHDIPALRIAGEATEEQILVAAVAYQDRHELLTKVLNDLYHLLRFETCKQIHKA 380

  Fly   393 LDVVLSAMDRHLKFKHMQISGSATLFYIVKGRDRSKFGALLRNHIIRTLLNGMEMHITDDTMLRN 457
            |||||||||:|::.|::|||||||||||||||::.|||..|:||||.||||||..|:|||||:||
Mosquito   381 LDVVLSAMDKHIRVKNIQISGSATLFYIVKGREKMKFGVPLKNHIIHTLLNGMSTHLTDDTMMRN 445

  Fly   458 GYLTLTQFHMPVDVLFEYERLIKILLHGVSKTEQEGFVQRIAIYLLNTLACQVDGRQKLFLGELG 522
            |.|||.||::|:||:||||||::|||||||..|||||||||||||||:|||||||.||||||:||
Mosquito   446 GCLTLCQFNIPLDVMFEYERLVQILLHGVSYREQEGFVQRIAIYLLNSLACQVDGSQKLFLGDLG 510

  Fly   523 VVSTMFTLIKDRLTRSVFDDVMEVAWSTMWNVTDETAINCKRFLDGRGMEYFLKCLHTFPDRDEL 587
            .:|||..||.|||:|.|||||||||||||||||||||.||:||||||||||||.||..|||||:|
Mosquito   511 AISTMLNLINDRLSRRVFDDVMEVAWSTMWNVTDETAKNCERFLDGRGMEYFLGCLKLFPDRDDL 575

  Fly   588 LRNMMGLLGNVAEVKWLRPKLMTQEFIEVFARLLDSLSDGIEVGGASASVVARVREREMASANHA 652
            |||||||||||||||.|||:|||.|||..|:.||||.|||||
Mosquito   576 LRNMMGLLGNVAEVKELRPRLMTTEFITEFSDLLDSSSDGIE----------------------- 617

  Fly   653 YLRFQVSYNAAGVLAHIASDGADAWTIKTPSREHVLERMVAAIQRWNIKSERNINYRSFEPILSL 717
                 ||||||||||||||||||||||..|:|..||.|||.||:||::.:|||||||||||||.|
Mosquito   618 -----VSYNAAGVLAHIASDGADAWTIARPTRYSVLVRMVEAIERWDLSAERNINYRSFEPILGL 677

  Fly   718 VRCYETPQCQHWAVWALANLTQVYPEKYCKLVEQENGIQILNELIEHESPYCEIKRIARLVIEQC 782
            :|||.||||||||||||||||:|||.|||::||||:|:::|.|||:|..||..:|.:|::|:..|
Mosquito   678 IRCYHTPQCQHWAVWALANLTKVYPTKYCRVVEQEHGVELLQELIDHPQPYPRLKELAQIVLTHC 742

  Fly   783 DSGSERM 789
            .:.||.|
Mosquito   743 RNLSEPM 749

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12084	NP_612112.1	leucine-rich repeat	110..135	CDD:275381	9/24 (38%)
		leucine-rich repeat	136..167	CDD:275381	18/30 (60%)
		leucine-rich repeat	168..189	CDD:275381	12/20 (60%)
		LRR	<184..>282	CDD:443914	53/97 (55%)
		leucine-rich repeat	190..213	CDD:275381	14/22 (64%)
LOC1276632	XP_061501346.1	None