DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ndf and PDP3

DIOPT Version :9

Sequence 1:	NP_001188767.1	Gene:	Ndf / 192507	FlyBaseID:	FBgn0043456	Length:	603	Species:	Drosophila melanogaster
Sequence 2:	NP_013560.3	Gene:	PDP3 / 851177	SGDID:	S000004447	Length:	304	Species:	Saccharomyces cerevisiae

Alignment Length:	261	Identity:	53/261 - (20%)
Similarity:	90/261 - (34%)	Gaps:	78/261 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 DLIWAKMKGFTPWPGMIVDPPLDLLS----QQRRANTKCVFFFGSRNFAWIEENNIKPFEGPWKE 84
            ||:..|:..|.|||.::.  |..||.    ::|::|...|.||....:.|.:.:.:|..:
Yeast     9 DLVLCKVGSFPPWPAVVF--PQRLLRNDVYRKRKSNCVAVCFFNDPTYYWEQPSRLKELD----- 66

  Fly    85 ELAKVSKPAAFRHAMTDIEKYI---DDPAEVDEQVNKSCGAPNHATEADFDK-IRDGLDSEEIVG 145
                          ...|..:|   ...|...|.||....|.|.   .||:. :::..:.|..:.
Yeast    67 --------------QDSIHNFILEHSKNANQRELVNAYKEAKNF---DDFNVFLQEKFEEENRLS 114

  Fly   146 EEATADGNNGVVAHVVGSPDEGDGLDVEINADSSASPVTSPAVTTKAAGKRTPKAKSV------- 203
            :....:.:.|  :.:|...|...|                   .||...||...:.|:
Yeast   115 DLKAFEKSEG--SKIVAGEDPFVG-------------------RTKVVNKRKKNSISIKEDPEDN 158

  Fly   204 AATSVKSTKGSAKSAQKRRTSAQQ-SPSGPSNAKRGKRDVSGEALQDADEASSTPTGRRRVETDA 267
            ..::.:.:|.:.|.::|:|.:|.. ..|...|.|:.|.|.|                 ||||...
Yeast   159 QKSNEEESKPNIKPSKKKRPTANSGGKSNSGNKKKVKLDYS-----------------RRVEISQ 206

  Fly   268 L 268
            |
Yeast   207 L 207

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ndf	NP_001188767.1	N_Pac_NP60	20..106	CDD:99897	18/85 (21%)
		NAD_binding_2	316..477	CDD:281445
		MmsB	319..597	CDD:224995
		NAD_binding_11	481..597	CDD:291499
PDP3	NP_013560.3	SPBC215_ISWI_like	5..96	CDD:99901	24/107 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002426
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000